{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T17:52:46Z","timestamp":1788976366446,"version":"build-2803163510"},"reference-count":29,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T00:00:00Z","timestamp":1097107200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2005,2]]},"abstract":"<jats:p><jats:italic>Trypanosoma (Herpetosoma) grosi<\/jats:italic>, which naturally parasitizes<jats:italic>Apodemus<\/jats:italic>spp., can experimentally infect Mongolian jirds (<jats:italic>Meriones unguiculatus<\/jats:italic>). Three isolates from<jats:italic>A. agrarius<\/jats:italic>,<jats:italic>A. peninsulae<\/jats:italic>, and<jats:italic>A. speciosus<\/jats:italic>(named SESUJI, HANTO, and AKHA isolates, respectively) of different geographical origin (AKHA from Japan, and the others from Vladivostok), exhibited different durations of parasitaemia in laboratory jirds (2 weeks for HANTO, and 3 weeks for the others). To assess the genetic background of these<jats:italic>T. grosi<\/jats:italic>isolates, their small (SSU) and large subunit (LSU) ribosomal RNA genes (rDNA) were sequenced along with those of 2 other<jats:italic>Herpetosoma<\/jats:italic>species from squirrels. The SSU rDNA sequences of these 3 species along with available sequences of 3 other<jats:italic>Herpetosoma<\/jats:italic>trypanosomes (<jats:italic>T. lewisi<\/jats:italic>,<jats:italic>T. musculi<\/jats:italic>and<jats:italic>T. microti)<\/jats:italic>seemed to reflect well the phylogenetic relationship of their hosts. Three isolates of<jats:italic>T. grosi<\/jats:italic>exhibited base changes at 2\u20136 positions of 2019-base 18S rDNA, at 5\u201329 positions of 1817\/1818-base 28S\u03b1 rDNA, or 1\u20135 positions of 1557\u20131559-base 28S\u03b2 rDNA, and none was separated from the other 2 isolates by rDNA nucleotide sequences. Since base changes of<jats:italic>Herpetosoma<\/jats:italic>trypanosomes at the level of inter- and intra-species might occur frequently in specified rDNA regions, the molecular analysis on these regions of rodent trypanosomes could help species\/strain differentiation and systematic revision of<jats:italic>Herpetosoma<\/jats:italic>trypanosome species, which must be more abundant than presently known.<\/jats:p>","DOI":"10.1017\/s0031182004006493","type":"journal-article","created":{"date-parts":[[2005,2,2]],"date-time":"2005-02-02T10:49:54Z","timestamp":1107341394000},"page":"157-167","source":"Crossref","is-referenced-by-count":24,"title":["Characterization of SSU and LSU rRNA genes of three<i>Trypanosoma (Herpetosoma) grosi<\/i>isolates maintained in Mongolian jirds"],"prefix":"10.1017","volume":"130","author":[{"given":"H.","family":"SATO","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"OSANAI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"KAMIYA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"OBARA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"JIANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Q.","family":"ZHEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"CHAI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"UNE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"ITO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2004,10,7]]},"reference":[{"key":"S0031182004006493_ref024","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(99)00016-8"},{"key":"S0031182004006493_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1119(84)90240-3"},{"key":"S0031182004006493_ref021","doi-asserted-by":"crossref","unstructured":"SPENCER, D. 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