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In this article we discuss the immunomodulatory effects of the phosphorylcholine-containing filarial nematode secreted glycoprotein ES-62. In particular we describe how it modulates intracellular signal transduction pathways in a number of different cells of the immune system, in particular B-lymphocytes, T-lymphocytes, macrophages and dendritic cells.<\/jats:p>","DOI":"10.1017\/s0031182005008164","type":"journal-article","created":{"date-parts":[[2005,11,11]],"date-time":"2005-11-11T09:15:47Z","timestamp":1131700547000},"page":"S63-S68","source":"Crossref","is-referenced-by-count":18,"title":["Subversion of immune cell signal transduction pathways by the secreted filarial nematode product, ES-62"],"prefix":"10.1017","volume":"130","author":[{"given":"W.","family":"HARNETT","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. 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