{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:59:45Z","timestamp":1783465185826,"version":"3.55.0"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2005,10,3]],"date-time":"2005-10-03T00:00:00Z","timestamp":1128297600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:p>SSU ribosomal sequences of trypanosomes from Brazilian cattle and water buffalo were used to infer phylogenetic relationships between non-pathogenic <jats:italic>T. theileri<\/jats:italic> and allied species parasitic in artiodactyls. <jats:italic>T. theileri<\/jats:italic> trypanosomes from distinct geographical regions in Brazil and from other countries were tightly clustered into the \u2018clade <jats:italic>T. theileri\u2019<\/jats:italic> distant from the \u2018<jats:italic>T. brucei<\/jats:italic> clade\u2019 of pathogenic parasites of artiodactyls, and also distinct from trypanosomes of other mammals. The existence of this monophyletic assemblage (<jats:italic>T. theileri<\/jats:italic> clade) composed only by isolates from artiodactyl species justifies the continued recognition of the subgenus <jats:italic>T<\/jats:italic>. (<jats:italic>Megatrypanum<\/jats:italic>) with <jats:italic>T. theileri<\/jats:italic> as its type species. Phylogenies based on SSU and ITS1 ribosomal sequences produced the same branching pattern with isolates from different mammalian hosts clustered in 5 lineages: A, related to water buffalo; B, C and D, to cattle; E, to fallow deer. The pattern of host specificity allied to some congruence between host and parasite phylogenies suggested association of these trypanosomes with their respective hosts. Segregation of cattle isolates into three lineages revealed an overall geographical structure. Moreover, positioning of trypanosomes infecting tabanids in the <jats:italic>T. theileri<\/jats:italic> clade is consistent with the role of these flies as important vectors of these trypanosomes.<\/jats:p>","DOI":"10.1017\/s0031182005008929","type":"journal-article","created":{"date-parts":[[2005,10,3]],"date-time":"2005-10-03T09:35:51Z","timestamp":1128332151000},"page":"215-224","source":"Crossref","is-referenced-by-count":71,"title":["Phylogeny of <i>Trypanosoma<\/i> (<i>Megatrypanum<\/i>) <i>theileri<\/i> and related trypanosomes reveals lineages of isolates associated with artiodactyl hosts diverging on SSU and ITS ribosomal sequences"],"prefix":"10.1017","volume":"132","author":[{"given":"A. 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