{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:31:59Z","timestamp":1791952319652,"version":"4.3.4"},"reference-count":49,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2006,10,19]],"date-time":"2006-10-19T00:00:00Z","timestamp":1161216000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:p><jats:italic>Ascaris<\/jats:italic> is a large parasitic roundworm (nematode) of the small intestine of humans and pigs, which causes the socio-economically important disease, ascariasis. To better understand the relationship of <jats:italic>Ascaris<\/jats:italic> between the 2 host species, recent studies in China have focused on investigating the genetics and epidemiology of <jats:italic>Ascaris<\/jats:italic> from humans and pigs using a mutation scanning-based approach. Findings provided support for a low level of gene flow between the human and porcine <jats:italic>Ascaris<\/jats:italic> populations. Extending the studies of genotypic variability within <jats:italic>Ascaris<\/jats:italic> from humans and pigs, experimental infections of mice and pigs with selected genotypes of <jats:italic>Ascaris<\/jats:italic> were carried out. Initial results indicate that there is a significant difference in the ability of <jats:italic>Ascaris<\/jats:italic> eggs of genotype G1 (derived from human) and G3 (derived from pig) to infect and establish as adults in pigs, supporting the difference in the frequencies of these genotypes in natural <jats:italic>Ascaris<\/jats:italic> populations between pigs and humans in China. Taken together, current information supports that there is limited cross-infection of <jats:italic>Ascaris<\/jats:italic> between humans and pigs in endemic regions and that pigs are not a significant reservoir of human infection with the adult nematode in such areas.<\/jats:p>","DOI":"10.1017\/s0031182006001521","type":"journal-article","created":{"date-parts":[[2006,10,19]],"date-time":"2006-10-19T14:05:56Z","timestamp":1161266756000},"page":"325-330","source":"Crossref","is-referenced-by-count":36,"title":["Recent insights into the epidemiology and genetics of <i>Ascaris<\/i> in China using molecular tools"],"prefix":"10.1017","volume":"134","author":[{"given":"W.","family":"PENG","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"YUAN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"HU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. 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