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Evidence that the molecule found in the parasite was antigenically and enzymatically homologous with a constituent of normal mouse plasma has been consolidated using a monospecific serum in immunoelectrophoresis and Western immunoblotting. The molecular size of the enzyme was found to be approximately 70\u00a0kDa and it was inhibited by a serine protease inhibitor, but not by inhibitors of other classes of protease. The enzymatic activity found in normal mouse serum was also found in normal rat serum, but not in sera from several other mammalian species.<\/jats:p>","DOI":"10.1017\/s0031182007003988","type":"journal-article","created":{"date-parts":[[2008,1,22]],"date-time":"2008-01-22T11:00:40Z","timestamp":1200999640000},"page":"467-472","source":"Crossref","is-referenced-by-count":7,"title":["An association between<i>Schistosoma mansoni<\/i>worms and an enzymatically-active protease\/peptidase in mouse blood"],"prefix":"10.1017","volume":"135","author":[{"given":"H.\u00a0Y.","family":"DARANI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.\u00a0J.","family":"DOENHOFF","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2008,1,22]]},"reference":[{"key":"S0031182007003988_ref023","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(73)90003-X"},{"key":"S0031182007003988_ref019","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761987000800037"},{"key":"S0031182007003988_ref008","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(88)90153-3"},{"key":"S0031182007003988_ref024","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.76.9.4350"},{"key":"S0031182007003988_ref020","doi-asserted-by":"crossref","first-page":"962","DOI":"10.4049\/jimmunol.131.2.962","article-title":"Evidence that schistosome MHC antigens are not synthesized by the parasite but are acquired from the host as intact glycoproteins","volume":"131","author":"Simpson","year":"1983","journal-title":"Journal of Immunology"},{"key":"S0031182007003988_ref018","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000081683"},{"key":"S0031182007003988_ref017","doi-asserted-by":"publisher","DOI":"10.1016\/0019-2791(65)90004-2"},{"key":"S0031182007003988_ref016","doi-asserted-by":"publisher","DOI":"10.1038\/365797a0"},{"key":"S0031182007003988_ref009","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.1986.tb00871.x"},{"key":"S0031182007003988_ref007","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00005344"},{"key":"S0031182007003988_ref006","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2005.12.010"},{"key":"S0031182007003988_ref005","first-page":"525","article-title":"Surface antigens on Schistosoma mansoni. 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