{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:35:31Z","timestamp":1761561331576},"reference-count":77,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2009,4,14]],"date-time":"2009-04-14T00:00:00Z","timestamp":1239667200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The development of<jats:italic>in vitro<\/jats:italic>culture systems that allow the maintenance, and support the development of<jats:italic>Echinococcus<\/jats:italic>,<jats:italic>Giardia<\/jats:italic>and<jats:italic>Cryptosporidium<\/jats:italic>in the laboratory have had a significant impact on their biology and taxonomy and the epidemiology of infections they cause. This short retrospective review demonstrates how radical shifts in our understanding have occurred as a result of being able to grow these organisms in culture, and how molecular tools have helped in the interpretation of such research that often reflects the observations of earlier workers.<\/jats:p>","DOI":"10.1017\/s0031182009005897","type":"journal-article","created":{"date-parts":[[2009,4,14]],"date-time":"2009-04-14T13:54:40Z","timestamp":1239717280000},"page":"1529-1535","source":"Crossref","is-referenced-by-count":9,"title":["<i>Echinococcus<\/i>,<i>Giardia<\/i>and<i>Cryptosporidium<\/i>: observational studies challenging accepted dogma"],"prefix":"10.1017","volume":"136","author":[{"given":"R. C. 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