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Seven, 8, and 8 pigs were necropsied at weeks 4, 8, and 14 post-start of infection (p.i.), respectively. The median numbers of worms in the colon were 538 (min\u2013max: 277\u2013618), 332 (14\u20131140) and 0 (0\u20134) at 4, 8, and 14 weeks p.i. respectively, suggesting an increased aggregation of the worms with time and acquisition of nearly sterile immunity. The serum levels of<jats:italic>T. suis<\/jats:italic>specific antibodies (IgG1, IgG2 and IgA) peaked at week 8 p.i. By week 14 p.i. the IgG2 and IgA antibody levels remained significantly elevated above the level of week 0. The population dynamics of<jats:italic>T. suis<\/jats:italic>trickle infections in pigs is discussed with focus on interpretation of diagnostic and epidemiological data of pigs, the use of pigs as a model for human<jats:italic>Trichuris trichiura<\/jats:italic>infections and the novel approach of using<jats:italic>T. suis<\/jats:italic>eggs in the treatment of patients with inflammatory bowel disease.<\/jats:p>","DOI":"10.1017\/s0031182009005976","type":"journal-article","created":{"date-parts":[[2009,4,16]],"date-time":"2009-04-16T08:24:50Z","timestamp":1239870290000},"page":"691-697","source":"Crossref","is-referenced-by-count":21,"title":["Population dynamics of<i>Trichuris suis<\/i>in trickle-infected pigs"],"prefix":"10.1017","volume":"136","author":[{"given":"P.","family":"NEJSUM","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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