{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:08:26Z","timestamp":1791266906512,"version":"4.1.0"},"reference-count":38,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2011,7,18]],"date-time":"2011-07-18T00:00:00Z","timestamp":1310947200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Experiments on hybridization between <jats:italic>Fasciola hepatica<\/jats:italic> and <jats:italic>Fasciola gigantica<\/jats:italic> were carried out to clarify whether a reproductive isolating mechanism appears between the two <jats:italic>Fasciola<\/jats:italic> species. Molecular evidence for hybridization was based on the DNA sequence of the internal transcribed spacer 1 (ITS1) region in nuclear ribosomal DNA, which differs between the species. The results suggested that there were not pre-mating but post-mating isolating mechanisms between the two species. However, viable adults of the hybrids F1 and F2 were produced from both parental <jats:italic>F. hepatica<\/jats:italic> and <jats:italic>F. gigantica<\/jats:italic>. The hybrids inherited phenotypic characteristics such as ratio of body length and width and infectivity to rats from parental <jats:italic>Fasciola hepatica<\/jats:italic> and <jats:italic>F. gigantica<\/jats:italic>. These findings suggest that reproductive isolation is incomplete between <jats:italic>Fasciola hepatica<\/jats:italic> and <jats:italic>F. gigantica<\/jats:italic>. Adults of the hybrids F1 and F2 were completely different in mode of reproduction from aspermic <jats:italic>Fasciola<\/jats:italic> forms that occur in Asia and seem to be offspring originated from hybridization between <jats:italic>F. hepatica<\/jats:italic> and <jats:italic>F. gigantica<\/jats:italic> and to reproduce parthenogenetically.<\/jats:p>","DOI":"10.1017\/s0031182011000965","type":"journal-article","created":{"date-parts":[[2011,7,18]],"date-time":"2011-07-18T09:20:35Z","timestamp":1310980835000},"page":"1278-1284","source":"Crossref","is-referenced-by-count":32,"title":["Hybridization experiments indicate incomplete reproductive isolating mechanism between <i>Fasciola hepatica<\/i> and <i>Fasciola gigantica<\/i>"],"prefix":"10.1017","volume":"138","author":[{"given":"T.","family":"ITAGAKI","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"ICHINOMIYA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"FUKUDA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"FUSYUKU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"CARMONA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2011,7,18]]},"reference":[{"key":"S0031182011000965_ref35","first-page":"113","volume-title":"Fasciolosis","author":"Torgerson","year":"1999"},{"key":"S0031182011000965_ref15","doi-asserted-by":"publisher","DOI":"10.1292\/jvms1939.51.853"},{"key":"S0031182011000965_ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2007.10.001"},{"key":"S0031182011000965_ref27","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-009-1459-0"},{"key":"S0031182011000965_ref18","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00023385"},{"key":"S0031182011000965_ref4","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.1967.5.3.139"},{"key":"S0031182011000965_ref31","doi-asserted-by":"publisher","DOI":"10.1038\/172110a0"},{"key":"S0031182011000965_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2006.06.003"},{"key":"S0031182011000965_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5769(00)00051-9"},{"key":"S0031182011000965_ref37","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00026456"},{"key":"S0031182011000965_ref23","doi-asserted-by":"publisher","DOI":"10.2307\/3282795"},{"key":"S0031182011000965_ref19","doi-asserted-by":"publisher","DOI":"10.1645\/0022-3395(2003)089[0416:FROANH]2.0.CO;2"},{"key":"S0031182011000965_ref5","first-page":"233","article-title":"Mating interactions between Schistosoma mansoni and S","volume":"125","author":"Cosgrove","year":"2002","journal-title":"margrebowiei. 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