{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T04:56:04Z","timestamp":1768712164552,"version":"3.49.0"},"reference-count":24,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2013,6,4]],"date-time":"2013-06-04T00:00:00Z","timestamp":1370304000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Decades of intensive anthelmintic treatment has caused equine large strongyles to become quite rare, while the cyathostomins have developed resistance to several drug classes. The larval culture has been associated with low to moderate negative predictive values for detecting <jats:italic>Strongylus vulgaris<\/jats:italic> infection. It is unknown whether detection of other large strongyle species can be statistically associated with presence of <jats:italic>S. vulgaris<\/jats:italic>. This remains a statistical challenge because of the rare occurrence of large strongyle species. This study used a modified Poisson regression to analyse a dataset for associations between <jats:italic>S. vulgaris<\/jats:italic> infection and simultaneous occurrence of <jats:italic>Strongylus edentatus<\/jats:italic> and <jats:italic>Triodontophorus<\/jats:italic> spp. In 663 horses on 42 Danish farms, the individual prevalences of <jats:italic>S. vulgaris, S. edentatus<\/jats:italic> and <jats:italic>Triodontophorus<\/jats:italic> spp. were 12%, 3% and 12%, respectively. Both <jats:italic>S. edentatus<\/jats:italic> and <jats:italic>Triodontophorus<\/jats:italic> spp. were significantly associated with <jats:italic>S. vulgaris<\/jats:italic> infection with relative risks above 1. Further, <jats:italic>S. edentatus<\/jats:italic> was associated with use of selective therapy on the farms, as well as negatively associated with anthelmintic treatment carried out within 6 months prior to the study. The findings illustrate that occurrence of <jats:italic>S. vulgaris<\/jats:italic> in larval cultures can be interpreted as indicative of other large strongyles being likely to be present.<\/jats:p>","DOI":"10.1017\/s0031182013000589","type":"journal-article","created":{"date-parts":[[2013,6,4]],"date-time":"2013-06-04T08:47:10Z","timestamp":1370335630000},"page":"1246-1251","source":"Crossref","is-referenced-by-count":9,"title":["Association between large strongyle genera in larval cultures \u2013 using rare-event Poisson regression"],"prefix":"10.1017","volume":"140","author":[{"given":"X.","family":"CAO","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. N.","family":"VIDYASHANKAR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. K.","family":"NIELSEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2013,6,4]]},"reference":[{"key":"S0031182013000589_ref2","first-page":"157","volume-title":"Equine Medicine and Surgery","author":"Drudge","year":"1972"},{"key":"S0031182013000589_ref12a","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(99)00092-8"},{"key":"S0031182013000589_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2004.08.001"},{"key":"S0031182013000589_ref10","first-page":"161","article-title":"Field tests of three salts of pyrantel [hydrochloride, tartrate, pamoate] against internal parasites of the horse [Strongylus vulgaris, Parascaris equorum, Strongylus edentatus]","volume":"36","author":"Lyons","year":"1975","journal-title":"American Journal of Veterinary Research"},{"key":"S0031182013000589_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2012.04.039"},{"key":"S0031182013000589_ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-005-0116-5"},{"key":"S0031182013000589_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(00)00266-1"},{"key":"S0031182013000589_ref13","first-page":"340","article-title":"Strongylus edentatus: development and lesions from ten weeks postinfection to patency","volume":"42","author":"McCraw","year":"1978","journal-title":"Canadian Journal of Comparative Medicine"},{"key":"S0031182013000589_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2010.08.007"},{"key":"S0031182013000589_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S0368-1742(48)80009-3"},{"key":"S0031182013000589_ref5","first-page":"429","article-title":"A method for recovery of gastrointestinal strongyle larvae","volume":"35","author":"Henriksen","year":"1983","journal-title":"Nordisk Veterinaer Medicin"},{"key":"S0031182013000589_ref1","first-page":"408","article-title":"Pyrantel resistant large strongyles in racehorses","volume":"145","author":"Coles","year":"1999","journal-title":"Veterinary Record"},{"key":"S0031182013000589_ref6","first-page":"732","article-title":"The changing world of worms \u2013 the rise of the cyathostomes and the decline of Strongylus vulgaris","volume":"12","author":"Herd","year":"1990","journal-title":"Compendium on Continuing Education for the Practicing Veterinarian"},{"key":"S0031182013000589_ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3292.2010.00084.x"},{"key":"S0031182013000589_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2008.04.026"},{"key":"S0031182013000589_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2005.10.020"},{"key":"S0031182013000589_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2009.09.043"},{"key":"S0031182013000589_ref18","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00004016"},{"key":"S0031182013000589_ref21","first-page":"129","article-title":"Die Entwicklungsdauer (Prepatent-periode) von Strongylus edentatus im Pferd","volume":"59","author":"Wetzel","year":"1952","journal-title":"Deutsche Tierartzliche Wochenschrift"},{"key":"S0031182013000589_ref22","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/24.5.1064"},{"key":"S0031182013000589_ref23","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwh090"},{"key":"S0031182013000589_ref20","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/126.2.346"},{"key":"S0031182013000589_ref3","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/S0034-5288(18)34017-7","article-title":"The life cycle of Strongylus vulgaris in the horse","volume":"13","author":"Duncan","year":"1972","journal-title":"Research in Veterinary Science"},{"key":"S0031182013000589_ref4","first-page":"65","article-title":"Die Pathogenese der thrombotisch-embolische Kolik des Pferdes","volume":"3","author":"Enigk","year":"1951","journal-title":"Monatsheft fur Tierheilkunde"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182013000589","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T20:14:45Z","timestamp":1556050485000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182013000589\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,4]]},"references-count":24,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S0031182013000589"],"URL":"https:\/\/doi.org\/10.1017\/s0031182013000589","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,4]]}}}