{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T10:01:59Z","timestamp":1792490519182,"version":"4.5.0"},"reference-count":61,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2013,10,11]],"date-time":"2013-10-11T00:00:00Z","timestamp":1381449600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>This study focuses on mapping the life cycle of<jats:italic>Cryptosporidium muris<\/jats:italic>in two laboratory rodents; BALB\/c mice and the southern multimammate rat<jats:italic>Mastomys coucha<\/jats:italic>, differing in their prepatent and patent periods. Both rodents were simultaneously experimentally inoculated with viable oocysts of<jats:italic>C. muris<\/jats:italic>(strain TS03). Animals were dissected and screened for the presence of the parasite using a combined morphological approach and nested PCR (SSU rRNA) at different times after inoculation. The occurrence of first developmental stages of<jats:italic>C. muris<\/jats:italic>in stomach was detected at 2\u00b75 days post-infection (dpi). The presence of Type II merogony, appearing 36\u00a0h later than Type I merogony, was confirmed in both rodents. Oocysts exhibiting different size and thickness of their wall were observed from 5\u00a0dpi onwards in stomachs of both host models. The early phase of parasitization in BALB\/c mice progressed rapidly, with a prepatent period of 7\u00b75\u201310 days; whereas in<jats:italic>M. coucha<\/jats:italic>, the developmental stages of<jats:italic>C. muris<\/jats:italic>were first observed 12\u00a0h later in comparison with BALB\/c mice and prepatent period was longer (18\u201321 days). Similarly, the patent periods of BALB\/c mice and<jats:italic>M. coucha<\/jats:italic>differed considerably, i.e. 10\u201315 days<jats:italic>vs<\/jats:italic>chronic infection throughout the life of the host, respectively.<\/jats:p>","DOI":"10.1017\/s0031182013001637","type":"journal-article","created":{"date-parts":[[2013,10,11]],"date-time":"2013-10-11T16:27:56Z","timestamp":1381508876000},"page":"287-303","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":22,"title":["Life cycle of<i>Cryptosporidium muris<\/i>in two rodents with different responses to 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