{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T02:28:03Z","timestamp":1789612083258,"version":"build-2803163510"},"reference-count":61,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p><jats:italic>Toxoplasma gondii<\/jats:italic>is a globally distributed parasite infecting humans and warm-blooded animals. Although many surveys have been conducted for<jats:italic>T. gondii<\/jats:italic>infection in mammals, little is known about the detailed distribution in localized natural populations. In this study, host genotype and spatial location were investigated in relation to<jats:italic>T. gondii<\/jats:italic>infection. Wood mice (<jats:italic>Apodemus sylvaticus<\/jats:italic>) were collected from 4 sampling sites within a localized peri-aquatic woodland ecosystem. Mice were genotyped using standard<jats:italic>A. sylvaticus<\/jats:italic>microsatellite markers and<jats:italic>T. gondii<\/jats:italic>was detected using 4 specific PCR-based markers: SAG1, SAG2, SAG3 and GRA6 directly from infected tissue. Of 126 wood mice collected, 44 samples were positive giving an infection rate of 34\u00b792% (95% CI: 27\u00b714\u201343\u00b759%). Juvenile, young adults and adults were infected at a similar prevalence, respectively, 7\/17 (41\u00b718%), 27\/65 (41\u00b754%) and 10\/44 (22\u00b772%) with no significant age-prevalence effect (<jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b723). Results of genetic analysis of the mice showed that the collection consists of 4 genetically distinct populations. There was a significant difference in<jats:italic>T. gondii<\/jats:italic>prevalence in the different genotypically derived mouse populations (<jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7035) but not between geographically defined populations (<jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b729). These data point to either a host genetic\/family influence on parasite infection or to parasite vertical transmission.<\/jats:p>","DOI":"10.1017\/s0031182014001760","type":"journal-article","created":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T13:11:53Z","timestamp":1417439513000},"page":"680-690","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":19,"title":["Prevalence of<i>Toxoplasma gondii<\/i>in localized populations of<i>Apodemus sylvaticus<\/i>is linked to population genotype not to population location"],"prefix":"10.1017","volume":"142","author":[{"given":"J.","family":"BAJNOK","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"BOYCE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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