{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:28:04Z","timestamp":1790620084447,"version":"4.1.0"},"reference-count":26,"publisher":"Cambridge University Press (CUP)","issue":"14","license":[{"start":{"date-parts":[[2015,10,7]],"date-time":"2015-10-07T00:00:00Z","timestamp":1444176000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>\n                    Utilization of chemical pesticide to control monogenean diseases is often restricted in many countries due to the development of pesticide resistance and concerns of chemical residues and environmental contamination. Thus, the use of antiparasitic agents from plants has been explored as a possible way for controlling monogenean infections. Extracts from\n                    <jats:italic>Cinnamomum cassia<\/jats:italic>\n                    were investigated under\n                    <jats:italic>in vivo<\/jats:italic>\n                    conditions against\n                    <jats:italic>Dactylogyrus intermedius<\/jats:italic>\n                    in goldfish. The two bioactive compounds, cinnamaldehyde and cinnamic acid, were identified using nuclear magnetic resonance and electrospray ionization mass spectrometry. The 48 h median effective concentrations (EC\n                    <jats:sub>50<\/jats:sub>\n                    ) for these compounds against\n                    <jats:italic>D. intermedius<\/jats:italic>\n                    were 0\u00b757 and 6\u00b732 mg L\n                    <jats:sup>\u22121<\/jats:sup>\n                    , respectively. The LD\n                    <jats:sub>50<\/jats:sub>\n                    of cinnamaldehyde and cinnamic acid were 13\u00b734 and 59\u00b766 mg L\n                    <jats:sup>\u22121<\/jats:sup>\n                    to goldfish in 48 h acute toxicity tests, respectively. These data confirm that cinnamaldehyde is effective against\n                    <jats:italic>D. intermedius<\/jats:italic>\n                    , and the cinnamaldehyde exhibits potential for the development of a candidate antiparasitic agent.\n                  <\/jats:p>","DOI":"10.1017\/s0031182015001031","type":"journal-article","created":{"date-parts":[[2015,10,7]],"date-time":"2015-10-07T02:57:32Z","timestamp":1444186652000},"page":"1744-1750","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":40,"title":["Anthelmintic efficacy of cinnamaldehyde and cinnamic acid from cortex cinnamon essential oil against\n                    <i>Dactylogyrus intermedius<\/i>"],"prefix":"10.1017","volume":"142","author":[{"given":"FEI","family":"LING","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CHAO","family":"JIANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GUANGLU","family":"LIU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MINGSHUANG","family":"LI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GAOXUE","family":"WANG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,10,7]]},"reference":[{"key":"S0031182015001031_ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-010-1799-9"},{"key":"S0031182015001031_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)97963-3"},{"key":"S0031182015001031_ref13","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.1190"},{"key":"S0031182015001031_ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-009-1659-7"},{"key":"S0031182015001031_ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-013-3600-3"},{"key":"S0031182015001031_ref22","first-page":"40","article-title":"Availability of medicines for fish","volume":"4","author":"Treves-Brown","year":"1999","journal-title":"Fish Veterinary Journal"},{"key":"S0031182015001031_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-011-2805-6"},{"key":"S0031182015001031_ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-012-2950-6"},{"key":"S0031182015001031_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2008.07.034"},{"key":"S0031182015001031_ref1","first-page":"103","volume-title":"Report About Fish Parasitic Diseases. Etudes et Recherches, Options Mediterranennes","author":"Alvarez-Pellitero","year":"2004"},{"key":"S0031182015001031_ref25","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-010-2010-z"},{"key":"S0031182015001031_ref5","doi-asserted-by":"publisher","DOI":"10.7589\/0090-3558-16.3.343"},{"key":"S0031182015001031_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3835(03)00238-6"},{"key":"S0031182015001031_ref16","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1017\/S0031182097001029","article-title":"Target sites of anthelmintics","volume":"114","author":"Martin","year":"1997","journal-title":"Parasitology"},{"key":"S0031182015001031_ref26","doi-asserted-by":"publisher","DOI":"10.3354\/dao02789"},{"key":"S0031182015001031_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2004.03.011"},{"key":"S0031182015001031_ref15","doi-asserted-by":"publisher","DOI":"10.1006\/jcat.1995.1115"},{"key":"S0031182015001031_ref6","doi-asserted-by":"publisher","DOI":"10.1002\/jat.2550040602"},{"key":"S0031182015001031_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2006.08.018"},{"key":"S0031182015001031_ref4","volume-title":"Probit Analysis","author":"Finney","year":"1971"},{"key":"S0031182015001031_ref3","volume-title":"Chinese Pharmacopoeia","year":"2010"},{"key":"S0031182015001031_ref11","unstructured":"Klinger R. and Floyd R. F. (2013). Introduction to freshwater fish parasites, document CIR716. Institute of Food and Agricultural Science Extension, University of Florida, Florida. http:\/\/edis.ifas.ufl.edu\/fa041."},{"key":"S0031182015001031_ref17","first-page":"644","article-title":"Investigations on the use of organic esters of phosphoric acid in the control of external parasites of farmed fish: II. Control of the invasion of parasites of Dactylogyrus and Gyrodactylus","volume":"22","author":"Prost","year":"1966","journal-title":"Medycyna Weterynaryjna"},{"key":"S0031182015001031_ref18","unstructured":"Reed P. , Francis-Floyd R. , Klinger R. and Petty D. (2012). Monogenean parasites of fish, document FA28. Institute of Food and Agricultural Science Extension, University of Florida, Florida. http:\/\/edis.ifas.ufl.edu\/fa033."},{"key":"S0031182015001031_ref19","doi-asserted-by":"publisher","DOI":"10.1007\/BF00926798"},{"key":"S0031182015001031_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(01)00184-0"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182015001031","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T05:19:05Z","timestamp":1599628745000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182015001031\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,7]]},"references-count":26,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S0031182015001031"],"URL":"https:\/\/doi.org\/10.1017\/s0031182015001031","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,7]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2015\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}