{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:40:26Z","timestamp":1791304826798,"version":"4.3.1"},"reference-count":59,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2016,5,13]],"date-time":"2016-05-13T00:00:00Z","timestamp":1463097600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>\n                    Two experiments studied the effects of dietary chicory against gastrointestinal nematodes in cattle. In Experiment (Exp.) 1, stabled calves were fed chicory silage (CHI\n                    <jats:sub>1<\/jats:sub>\n                    ;\n                    <jats:italic>n<\/jats:italic>\n                    = 9) or ryegrass\/clover hay (CTL\n                    <jats:sub>1<\/jats:sub>\n                    ;\n                    <jats:italic>n<\/jats:italic>\n                    = 6) with balanced protein\/energy intakes between groups. After 16 days, all calves received 10 000\n                    <jats:italic>Ostertagia ostertagi<\/jats:italic>\n                    and 66 000\n                    <jats:italic>Cooperia oncophora<\/jats:italic>\n                    third-stage larvae (L3) [day (D) 0 post-infection (p.i.)]. In Exp. 2, calves were assigned to pure chicory (CHI\n                    <jats:sub>2<\/jats:sub>\n                    ;\n                    <jats:italic>n<\/jats:italic>\n                    =10) or ryegrass\/clover (CTL\n                    <jats:sub>2<\/jats:sub>\n                    ;\n                    <jats:italic>n<\/jats:italic>\n                    = 10) pastures. After 7 days, animals received 20 000\n                    <jats:italic>O. ostertagi<\/jats:italic>\n                    L3\/calf (D0 p.i.) and were moved regularly preventing pasture-borne infections. Due to poor regrowth of the chicory pasture, CHI\n                    <jats:sub>2<\/jats:sub>\n                    was supplemented with chicory silage. At D40 p.i. (Exp. 1) and D35 p.i. (Exp. 2) calves were slaughtered for worm recovery. In Exp.1, fecal egg counts (FEC) were similar between groups. However,\n                    <jats:italic>O. ostertagi<\/jats:italic>\n                    counts were significantly reduced in CHI\n                    <jats:sub>1<\/jats:sub>\n                    by 60% (geometric mean;\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0\u00b701), whereas\n                    <jats:italic>C. oncophora<\/jats:italic>\n                    burdens were unaffected (\n                    <jats:italic>P<\/jats:italic>\n                    = 0\u00b712). In Exp. 2, FEC were markedly lowered in CHI\n                    <jats:sub>2<\/jats:sub>\n                    from D22 p.i onwards (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0\u00b701).\n                    <jats:italic>Ostertagia ostertagi<\/jats:italic>\n                    adult burdens were significantly reduced in CHI\n                    <jats:sub>2<\/jats:sub>\n                    by 66% (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0\u00b7001). Sesquiterpene lactones were identified only in chicory (fresh\/silage). Chicory shows promise as an anti-\n                    <jats:italic>Ostertagia<\/jats:italic>\n                    feed for cattle and further studies should investigate its on-farm use.\n                  <\/jats:p>","DOI":"10.1017\/s0031182016000706","type":"journal-article","created":{"date-parts":[[2016,5,13]],"date-time":"2016-05-13T05:11:36Z","timestamp":1463116296000},"page":"1279-1293","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":55,"title":["Anthelmintic effects of forage chicory (\n                    <i>Cichorium intybus<\/i>\n                    ) against gastrointestinal nematode parasites in experimentally infected cattle"],"prefix":"10.1017","volume":"143","author":[{"given":"MIGUEL","family":"PE\u00d1A-ESPINOZA","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"STIG M.","family":"THAMSBORG","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"OLIVIER","family":"DESRUES","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"TINA V. A.","family":"HANSEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HEIDI L.","family":"ENEMARK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2016,5,13]]},"reference":[{"key":"S0031182016000706_ref54","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4017(93)90223-A"},{"key":"S0031182016000706_ref36","volume-title":"R: A Language and Environment for Statistical Computing","year":"2015"},{"key":"S0031182016000706_ref16","first-page":"163","article-title":"Anthelmintic resistance to ivermectin and moxidectin in gastrointestinal nematodes of cattle in Europe","volume":"5","author":"Geurden","year":"2015","journal-title":"International Journal for Parasitology: Drugs and Drug Resistance"},{"key":"S0031182016000706_ref57","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2004.07.012"},{"key":"S0031182016000706_ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2494.2011.00801.x"},{"key":"S0031182016000706_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2012.04.079"},{"key":"S0031182016000706_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2014.11.019"},{"key":"S0031182016000706_ref33","doi-asserted-by":"publisher","DOI":"10.1080\/09064700310001964"},{"key":"S0031182016000706_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4922(01)01900-6"},{"key":"S0031182016000706_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2010.02.036"},{"key":"S0031182016000706_ref17","doi-asserted-by":"publisher","DOI":"10.1021\/jf304158m"},{"key":"S0031182016000706_ref55","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2014.11.001"},{"key":"S0031182016000706_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2014.03.017"},{"key":"S0031182016000706_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2015.06.026"},{"key":"S0031182016000706_ref11","doi-asserted-by":"publisher","DOI":"10.1021\/jf052546g"},{"key":"S0031182016000706_ref32","doi-asserted-by":"publisher","DOI":"10.1080\/00288233.1993.10417734"},{"key":"S0031182016000706_ref31","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1017\/S003118200007030X","article-title":"The regulation of egg output by Ostertagia ostertagi in calves infected once only","volume":"59","author":"Michel","year":"1969","journal-title":"Parasitology"},{"key":"S0031182016000706_ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2007.01.009"},{"key":"S0031182016000706_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8741(03)00145-4"},{"key":"S0031182016000706_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2004.09.031"},{"key":"S0031182016000706_ref3","doi-asserted-by":"publisher","DOI":"10.1017\/S002185969800584X"},{"key":"S0031182016000706_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5288(98)90153-9"},{"key":"S0031182016000706_ref4","volume-title":"Magen-Darm-Nematoden des Rindes, Diagnostischer Atlas","author":"Barth","year":"1991"},{"key":"S0031182016000706_ref10","first-page":"103","article-title":"Chemical and biological stability of artemisinin in bovine rumen fluid and its kinetics in goats (Capra hircus)","volume":"17","author":"Ferreira","year":"2008","journal-title":"Brazil Journal of Veterinary Parasitology"},{"key":"S0031182016000706_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2011.03.013"},{"key":"S0031182016000706_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(97)00104-0"},{"key":"S0031182016000706_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2008.10.010"},{"key":"S0031182016000706_ref21","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1371731"},{"key":"S0031182016000706_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2006.04.004"},{"key":"S0031182016000706_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.eja.2005.10.007"},{"key":"S0031182016000706_ref25","doi-asserted-by":"publisher","DOI":"10.1080\/09064702.2015.1023341"},{"key":"S0031182016000706_ref27","doi-asserted-by":"publisher","DOI":"10.1016\/0165-2427(92)90186-T"},{"key":"S0031182016000706_ref28","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(02)00412-0"},{"key":"S0031182016000706_ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2006.01.029"},{"key":"S0031182016000706_ref30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0086259"},{"key":"S0031182016000706_ref37","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(00)83015-0"},{"key":"S0031182016000706_ref38","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.2011.01313.x"},{"key":"S0031182016000706_ref39","volume-title":"Epidemiology, Diagnosis and Control of Helminth Parasites of Swine","author":"Roepstorff","year":"1998"},{"key":"S0031182016000706_ref52","doi-asserted-by":"publisher","DOI":"10.4102\/ojvr.v80i1.539"},{"key":"S0031182016000706_ref40","doi-asserted-by":"publisher","DOI":"10.1080\/03015521.1986.10426133"},{"key":"S0031182016000706_ref41","doi-asserted-by":"publisher","DOI":"10.1016\/j.anifeedsci.2012.07.023"},{"key":"S0031182016000706_ref42","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1084620"},{"key":"S0031182016000706_ref58","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-4758(96)40009-6"},{"key":"S0031182016000706_ref43","doi-asserted-by":"publisher","DOI":"10.1080\/00288233.1995.9513124"},{"key":"S0031182016000706_ref49","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2004.11.013"},{"key":"S0031182016000706_ref45","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2014.06.024"},{"key":"S0031182016000706_ref46","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2010.11.008"},{"key":"S0031182016000706_ref47","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-35982010001300041"},{"key":"S0031182016000706_ref50","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182005009194"},{"key":"S0031182016000706_ref51","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(96)00120-8"},{"key":"S0031182016000706_ref20","first-page":"392","article-title":"A simple flotation and McMaster technique","volume":"28","author":"Henriksen","year":"1975","journal-title":"Nordisk Veterinaer Medicin"},{"key":"S0031182016000706_ref53","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(01)00431-9"},{"key":"S0031182016000706_ref56","doi-asserted-by":"publisher","DOI":"10.3920\/978-90-8686-718-9"},{"key":"S0031182016000706_ref59","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4017(95)00806-2"},{"key":"S0031182016000706_ref34","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4922(03)00149-1"},{"key":"S0031182016000706_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2113(05)88005-8"},{"key":"S0031182016000706_ref44","doi-asserted-by":"publisher","DOI":"10.4141\/cjas-2014-169"},{"key":"S0031182016000706_ref48","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2494.1963.tb00335.x"},{"key":"S0031182016000706_ref35","first-page":"191","article-title":"Sesquiterpene lactone containing extracts from two cultivars of forage chicory (Cichorium intybus) show distinctive chemical profiles and in vitro activity against Ostertagia ostertagi","volume":"5","author":"Pe\u00f1a-Espinoza","year":"2015","journal-title":"International Journal for Parasitology: Drugs and Drug Resistance"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182016000706","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,7]],"date-time":"2019-09-07T12:15:46Z","timestamp":1567858546000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182016000706\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,13]]},"references-count":59,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S0031182016000706"],"URL":"https:\/\/doi.org\/10.1017\/s0031182016000706","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,13]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2016\u00a0This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}