{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T09:36:10Z","timestamp":1789810570228,"version":"4.0.1"},"reference-count":131,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T00:00:00Z","timestamp":1478736000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>In recent years, a malaria infection of humans in South East Asia, originally diagnosed as a known human-infecting species,<jats:italic>Plasmodium malariae<\/jats:italic>, has been identified as a simian parasite,<jats:italic>Plasmodium knowlesi.<\/jats:italic>This species had been subject to considerable investigation in monkeys since the 1930s. With the development of continuous culture of the erythrocytic stages of the human malarial parasite,<jats:italic>Plasmodium falciparum<\/jats:italic>in 1976, the emphasis in research shifted away from knowlesi. However, its importance as a human pathogen has provoked a renewed interest in<jats:italic>P. knowlesi<\/jats:italic>, not least because it too can be maintained in continuous culture and thus provides an experimental model. In fact, this parasite species has a long history in malaria research, and the purpose of this chapter is to outline approximately the first 50 years of this history.<\/jats:p>","DOI":"10.1017\/s0031182016001888","type":"journal-article","created":{"date-parts":[[2016,11,10]],"date-time":"2016-11-10T08:09:48Z","timestamp":1478765388000},"page":"6-17","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":12,"title":["The role of<i>Plasmodium knowlesi<\/i>in the history of malaria research"],"prefix":"10.1017","volume":"145","author":[{"given":"G. A.","family":"BUTCHER","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. 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