{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:49:41Z","timestamp":1761490181543},"reference-count":41,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2017,1,20]],"date-time":"2017-01-20T00:00:00Z","timestamp":1484870400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Soil-transmitted helminth (STH) infections are widely distributed in tropical and subtropical areas, including Brazil. We performed a nationwide population-based study including all deaths in Brazil from 2000 to 2011, in which STHs (ascariasis, trichuriasis and\/or hookworm infection) were mentioned on death certificates, either as underlying or as associated causes of death. Epidemiological characteristics, time trends and spatial analysis of STH-related mortality were analysed. STHs was identified on 853\/12 491 280 death certificates: 827 (97\u00b70%) deaths related to ascariasis, 25 (2\u00b79%) to hookworm infections, and 1 (0\u00b71%) to trichuriasis. The average annual age-adjusted mortality rate was 0\u00b734\/1 000 000 inhabitants (95% confidence interval: 0\u00b727\u20130\u00b744). Females, children &lt;10 years of age, indigenous ethnic groups and residents in the Northeast region had highest STH-related mortality rates. Nationwide mortality decreased significantly over time (annual percent change: \u22125\u00b77%; 95% CI: \u22126\u00b79 to \u22124\u00b74), with regional differences. We identified spatial high-risk clusters for STH-related mortality mainly in the North, Northeast and South regions. Diseases of the digestive system and infectious\/parasitic diseases were the most commonly associated causes of death mentioned in the STH-related deaths. Despite decreasing mortality in Brazil, a considerable number of deaths is caused by STHs, with ascariasis responsible for the vast majority. There were marked regional differences, affecting mainly children and vulnerable populations.<\/jats:p>","DOI":"10.1017\/s0031182016002341","type":"journal-article","created":{"date-parts":[[2017,1,20]],"date-time":"2017-01-20T09:15:18Z","timestamp":1484903718000},"page":"669-679","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":14,"title":["Epidemiology of soil-transmitted helminthiases-related mortality in Brazil"],"prefix":"10.1017","volume":"144","author":[{"given":"FRANCISCO R.","family":"MARTINS-MELO","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"JR","given":"ALBERTO N.","family":"RAMOS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CARLOS H.","family":"ALENCAR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MAURIC\u00c9LIA 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