{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:50:18Z","timestamp":1792680618619,"version":"4.5.0"},"reference-count":31,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2019,11,21]],"date-time":"2019-11-21T00:00:00Z","timestamp":1574294400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Schistosomiasis is a neglected tropical disease, though it is highly prevalent in many parts of sub-Saharan Africa. While <jats:italic>Schistosoma haematobium-bovis<\/jats:italic> hybrids have been reported in West Africa, no data about <jats:italic>Schistosoma<\/jats:italic> hybrids in humans are available from C\u00f4te d'Ivoire. This study aimed to identify and quantify <jats:italic>S. haematobium-bovis<\/jats:italic> hybrids among schoolchildren in four localities of C\u00f4te d'Ivoire. Urine samples were collected and examined by filtration to detect <jats:italic>Schistosoma<\/jats:italic> eggs. Eggs were hatched and 503 miracidia were individually collected and stored on Whatman<jats:sup>\u00ae<\/jats:sup> FTA cards for molecular analysis. Individual miracidia were molecularly characterized by analysis of mitochondrial cox1 and nuclear internal transcribed spacer 2 (ITS 2) DNA regions. A mitochondrial cox1-based diagnostic polymerase chain reaction was performed on 459 miracidia, with 239 (52.1%) exhibiting the typical band for <jats:italic>S. haematobium<\/jats:italic> and 220 (47.9%) the <jats:italic>S. bovis<\/jats:italic> band. The cox1 and ITS 2 amplicons were Sanger sequenced from 40 randomly selected miracidia to confirm species and hybrids status. Among the 33 cox1 sequences analysed, we identified 15 <jats:italic>S. haematobium<\/jats:italic> sequences (45.5%) belonging to seven haplotypes and 18 <jats:italic>S. bovis<\/jats:italic> sequences (54.5%) belonging to 12 haplotypes. Of 40 ITS 2 sequences analysed, 31 (77.5%) were assigned to pure <jats:italic>S. haematobium<\/jats:italic>, four (10.0%) to pure <jats:italic>S. bovis<\/jats:italic> and five (12.5%) to <jats:italic>S. haematobium-bovis<\/jats:italic> hybrids. Our findings suggest that <jats:italic>S. haematobium-bovis<\/jats:italic> hybrids are common in C\u00f4te d'Ivoire. Hence, intense prospection of domestic and wild animals is warranted to determine whether zoonotic transmission occurs.<\/jats:p>","DOI":"10.1017\/s0031182019001549","type":"journal-article","created":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T06:08:47Z","timestamp":1573798127000},"page":"287-294","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":57,"title":["High prevalence of <i>Schistosoma haematobium<\/i> \u00d7 <i>Schistosoma bovis<\/i> hybrids in schoolchildren in C\u00f4te d'Ivoire"],"prefix":"10.1017","volume":"147","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7589-9175","authenticated-orcid":false,"given":"Etienne 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