{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T14:48:42Z","timestamp":1784731722945,"version":"3.55.0"},"reference-count":37,"publisher":"Cambridge University Press (CUP)","issue":"14","license":[{"start":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T00:00:00Z","timestamp":1598227200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hookworms are some of the most widespread of the soil-transmitted helminths (STH) with an estimated 438.9 million people infected. Until relatively recently <jats:italic>Ancylostoma ceylanicum<\/jats:italic> was regarded as a rare cause of hookworm infection in humans, with little public health relevance. However, recent advances in molecular diagnostics have revealed a much higher prevalence of this zoonotic hookworm than previously thought, particularly in Asia. This study examined the prevalence of STH and <jats:italic>A. ceylanicum<\/jats:italic> in the municipalities of Palapag and Laoang in the Philippines utilizing real-time polymerase chain reaction (PCR) on stool samples previously collected as part of a cross-sectional survey of schistosomiasis japonica. Prevalence of hookworm in humans was high with 52.8% (<jats:italic>n<\/jats:italic> = 228\/432) individuals positive for any hookworm, 34.5% (<jats:italic>n<\/jats:italic> = 149\/432) infected with <jats:italic>Necator americanus<\/jats:italic>, and 29.6% (<jats:italic>n<\/jats:italic> = 128\/432) with <jats:italic>Ancylostoma<\/jats:italic> spp; of these, 34 were PCR-positive for <jats:italic>A. ceylanicum.<\/jats:italic> Considering dogs, 12 (<jats:italic>n<\/jats:italic> = 33) were PCR-positive for <jats:italic>A. ceylanicum<\/jats:italic>. This is the first study to utilize molecular diagnostics to identify <jats:italic>A. ceylanicum<\/jats:italic> in the Philippines with both humans and dogs infected. Control and elimination of this zoonotic hookworm will require a multifaceted approach including chemotherapy of humans, identification of animal reservoirs, improvements in health infrastructure, and health education to help prevent infection.<\/jats:p>","DOI":"10.1017\/s0031182020001547","type":"journal-article","created":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T02:58:09Z","timestamp":1598237889000},"page":"1718-1722","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":16,"title":["Molecular identification of <i>Ancylostoma ceylanicum<\/i> in the Philippines"],"prefix":"10.1017","volume":"147","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8746-4796","authenticated-orcid":false,"given":"Oyime P.","family":"Aula","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6443-1449","authenticated-orcid":false,"given":"Donald 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