{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T14:59:41Z","timestamp":1781967581085,"version":"3.54.5"},"reference-count":43,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T00:00:00Z","timestamp":1625443200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"funder":[{"DOI":"10.13039\/100009534","name":"Universidad Aut\u00f3noma Chapingo","doi-asserted-by":"publisher","award":["20010-C-67"],"award-info":[{"award-number":["20010-C-67"]}],"id":[{"id":"10.13039\/100009534","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of this study was to evaluate the effectiveness of the main anthelmintics used for the control of trematodes in cattle in an endemic area in the humid Mexican tropics. A diagnostic study was carried out in nine cattle farms to determine the prevalence of flukes through faecal examination. Only three farms with more than 20 cows positive to trematodes were chosen to determine the effectiveness of commercial anthelmintics (triclabendazole, TCBZ; ivermectin + closantel, (IVM + CLOS); IVM + clorsulon, (CLORS); nitroxynil, NITROX). The prevalence of <jats:italic>Fasciola hepatica<\/jats:italic> was 27.1% and 29.6% of paramphistomes. The faecal egg count of trematodes ranged from 0.0 to 12.2 eggs per gram of faeces. The highest effectiveness against <jats:italic>F. hepatica<\/jats:italic> was 96.7%, and 92.7% against paramphistomes. NITROX was the most effective in the control of trematodes, while other products, such as IVM + CLORS and TCBZ obtained values lower than 90%, which puts sustainable trematode control at risk. The presence of trematodes was observed on most farms, although the prevalence per herd was highly variable, which indicates that the trematodes <jats:italic>F. hepatic<\/jats:italic>a and paramphistomes are endemic to the region and a suitable management programme is suggested to control infections caused by these parasites.<\/jats:p>","DOI":"10.1017\/s0031182021001153","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T08:51:41Z","timestamp":1625475101000},"page":"1458-1466","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":11,"title":["Assessment of anthelmintic effectiveness to control <i>Fasciola hepatica<\/i> and paramphistome mixed infection in cattle in the humid tropics of Mexico"],"prefix":"10.1017","volume":"148","author":[{"given":"Rodrigo","family":"Ico-G\u00f3mez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0333-7787","authenticated-orcid":false,"given":"Roberto","family":"Gonz\u00e1lez-Gardu\u00f1o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Ortiz-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8892-6390","authenticated-orcid":false,"given":"Juan J.","family":"Mosqueda-Gualito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ever del J.","family":"Flores-Santiago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"Sosa-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abel A.","family":"Salazar-Tapia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2021,7,5]]},"reference":[{"key":"S0031182021001153_ref40","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2016.01.010"},{"key":"S0031182021001153_ref43","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2019.03.005"},{"key":"S0031182021001153_ref20","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182016001797"},{"key":"S0031182021001153_ref34","first-page":"100364","article-title":"Prevalence and risk factors associated with liver fluke Fasciola hepatica in cattle and sheep in three municipalities in the Colombian Northeastern Mountains","volume":"19","author":"Pinilla","year":"2020","journal-title":"Veterinary Parasitology: Regional Studies and Reports"},{"key":"S0031182021001153_ref35","doi-asserted-by":"publisher","DOI":"10.4236\/pp.2019.1011041"},{"key":"S0031182021001153_ref27","first-page":"172","article-title":"First report of closantel treatment failure against Fasciola hepatica in cattle","volume":"5","author":"Novobilsk\u00fd","year":"2015","journal-title":"International Journal for Parasitology: Drugs and Drug Resistance"},{"key":"S0031182021001153_ref14","doi-asserted-by":"publisher","DOI":"10.12968\/live.2016.21.1.30"},{"key":"S0031182021001153_ref25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.13188\/2325-4645.1000051","article-title":"Review on triclabendazole resistance in Fasciola","volume":"8","author":"Merachew","year":"2020","journal-title":"Journal of Veterinary Science and Medicine"},{"key":"S0031182021001153_ref41","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjbas.2013.09.006"},{"key":"S0031182021001153_ref17","first-page":"1","article-title":"Evaluation of anthelmintic drugs against egg development of rumen flukes recovered from cattle raised in the humid tropics of Mexico","volume":"4","author":"Gonz\u00e1lez-Gardu\u00f1o","year":"2020","journal-title":"Journal of Helminthology"},{"key":"S0031182021001153_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2013.10.019"},{"key":"S0031182021001153_ref39","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2012.07.028"},{"key":"S0031182021001153_ref18","first-page":"43","article-title":"Comparative efficacy of ivermectin plus clorsulon and nitroxynil against naturally infected cattle","volume":"29","author":"Islam","year":"2013","journal-title":"Eurasian Journal of Veterinary Sciences"},{"key":"S0031182021001153_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2013.06.011"},{"key":"S0031182021001153_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2014.10.033"},{"key":"S0031182021001153_ref5","first-page":"48","article-title":"Confirmation of Fasciola hepatica resistant to triclabendazole in naturally infected Australian beef and dairy cattle","volume":"4","author":"Brockwell","year":"2014","journal-title":"International Journal for Parasitology: Drugs and Drug Resistance"},{"key":"S0031182021001153_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2019.109019"},{"key":"S0031182021001153_ref30","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-018-2965-7"},{"key":"S0031182021001153_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2016.03.002"},{"key":"S0031182021001153_ref36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1987.tb06060.x"},{"key":"S0031182021001153_ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-003-0863-0"},{"key":"S0031182021001153_ref16","doi-asserted-by":"publisher","DOI":"10.15381\/rivep.v27i4.12572"},{"key":"S0031182021001153_ref3","doi-asserted-by":"publisher","DOI":"10.1136\/vr.d85"},{"key":"S0031182021001153_ref10","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X17000402"},{"key":"S0031182021001153_ref38","doi-asserted-by":"publisher","DOI":"10.2478\/s11687-008-0012-5"},{"key":"S0031182021001153_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2010.10.023"},{"key":"S0031182021001153_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4017(85)90004-4"},{"key":"S0031182021001153_ref31","doi-asserted-by":"publisher","DOI":"10.22319\/rmcp.v11i2.5173"},{"key":"S0031182021001153_ref32","first-page":"87","article-title":"Prevalencia de fascioliasis y paramfistomiasis en el ganado lechero de Oxapampa, Pasco","volume":"21","author":"Paucar","year":"2010","journal-title":"Revista de Investigaciones Veterinarias del Per\u00fa"},{"key":"S0031182021001153_ref1","doi-asserted-by":"publisher","DOI":"10.14419\/ijpt.v3i1.4494"},{"key":"S0031182021001153_ref29","doi-asserted-by":"publisher","DOI":"10.14202\/vetworld.2020.687-694"},{"key":"S0031182021001153_ref42","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2013.04.004"},{"key":"S0031182021001153_ref6","unstructured":"CONAGUA (2021) Servicio Meteorol\u00f3gico Nacional. Normales climatol\u00f3gicas. Available at http:\/\/smn.cna.gob.mx\/climatologia\/normales\/estacion\/tab\/NORMAL27068.TXT."},{"key":"S0031182021001153_ref28","first-page":"141","article-title":"Assessment of flukicide efficacy against Fasciola hepatica in sheep in Sweden in the absence of a standardised test","volume":"6","author":"Novobilsk\u00fd","year":"2016","journal-title":"International Journal for Parasitology: Drugs and Drug Resistance"},{"key":"S0031182021001153_ref11","first-page":"39","article-title":"Drug resistance in liver flukes","volume":"12","author":"Fairweather","year":"2020","journal-title":"International Journal for Parasitology: Drugs and Drug Resistance"},{"key":"S0031182021001153_ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-020-06705-4"},{"key":"S0031182021001153_ref9","doi-asserted-by":"publisher","DOI":"10.1007\/BF00012228"},{"key":"S0031182021001153_ref37","doi-asserted-by":"publisher","DOI":"10.1590\/s1984-296120180089"},{"key":"S0031182021001153_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2012.04.019"},{"key":"S0031182021001153_ref33","first-page":"161","article-title":"Prevalencia de trematodes de la familia Paramphistomatidae en bovinos del distrito de Yurimaguas, provincia de alto Amazonas","volume":"21","author":"Pinedo","year":"2010","journal-title":"Revista de Investigaciones Veterinarias del Per\u00fa"},{"key":"S0031182021001153_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2011.11.049"},{"key":"S0031182021001153_ref19","doi-asserted-by":"publisher","DOI":"10.1007\/BF00010137"},{"key":"S0031182021001153_ref26","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-018-3114-z"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182021001153","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T09:55:36Z","timestamp":1685354136000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182021001153\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,5]]},"references-count":43,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["S0031182021001153"],"URL":"https:\/\/doi.org\/10.1017\/s0031182021001153","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,5]]},"assertion":[{"value":"Copyright \u00a9 The Author(s), 2021. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}