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Besides, the <jats:italic>T. vivax<\/jats:italic> viability in 109 injectable veterinary drugs (antibiotics, antiparasitics, reproductive hormones, vitamin complex and derivatives, vaccines, anaesthetics, anti-inflammatory\/antipyretics, antitoxics). In the field assay, four groups were performed: T01, T02 and T03 animals that received saline solution with the same syringe and needle contaminated with <jats:italic>T. vivax via<\/jats:italic> SC, IM and IV routes, respectively, and T04 control animals that received only saline solution with the same syringe and needle IV. In the laboratory, drugs had their pH measured and <jats:italic>T. vivax<\/jats:italic> viability verified. The number of cattle infected with <jats:italic>T. vivax via<\/jats:italic> SC (3\/20) was lower (<jats:italic>P<\/jats:italic> \u2264 0.05) compared to <jats:italic>via<\/jats:italic> IM (9\/20), which was lower (<jats:italic>P<\/jats:italic> \u2264 0.05) compared to IV (15\/20). The solution pH did not influence <jats:italic>T. vivax<\/jats:italic> viability. In 44% (48\/109) of the products, <jats:italic>T. vivax<\/jats:italic> remained viable regardless of time, stooding out that in 100% of oxytocins the protozoan was verified, at some evaluation times. The mean of <jats:italic>T. vivax<\/jats:italic> quantified in foot-and-mouth and brucellosis vaccines and in doramectin-based products were higher (<jats:italic>P<\/jats:italic> \u2264 0.05) than found in blood + saline solution.<\/jats:p>","DOI":"10.1017\/s003118202100175x","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T11:21:25Z","timestamp":1636456885000},"page":"270-282","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":10,"title":["How many cattle can be infected by <i>Trypanosoma vivax<\/i> by reusing the same needle and syringe, and what is the viability time of this protozoan in injectable veterinary products?"],"prefix":"10.1017","volume":"149","author":[{"given":"Rubens Dias","family":"de Melo Junior","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiago Souza","family":"Azeredo Bastos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana Maffini","family":"Heller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Fellipe Monteiro","family":"Couto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina Mar\u00eda Beltr\u00e1n","family":"Zapa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alliny Souza","family":"de Assis Cavalcante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo Bueno","family":"Cruvinel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Eduardo","family":"Nicaretta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haryie Vict\u00f3ria","family":"Iuasse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0813-3054","authenticated-orcid":false,"given":"Lorena Lopes","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vando Ed\u00e9sio","family":"Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme Rocha Lino","family":"de Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiano Ant\u00f4nio","family":"Cadioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8009-8436","authenticated-orcid":false,"given":"Welber Daniel Zanetti","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2021,11,9]]},"reference":[{"key":"S003118202100175X_ref28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0016957"},{"key":"S003118202100175X_ref13","first-page":"100466","article-title":"Parasitological and clinical-pathological findings in twelve outbreaks of acute trypanosomiasis in dairy cattle in Rio de Janeiro state, Brazil","volume":"22","author":"Costa","year":"2020","journal-title":"Veterinary Parasitology: Regional Studies and Reports"},{"key":"S003118202100175X_ref6","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182020001006"},{"key":"S003118202100175X_ref20","first-page":"1","article-title":"Trypanosoma vivax em bovino leiteiro","volume":"46","author":"Lopes","year":"2018","journal-title":"Acta Scientific Veterinary"},{"key":"S003118202100175X_ref32","first-page":"2550","article-title":"First report of Trypanosoma vixax in bovines in the State of Rio Grande do Sul","volume":"39","author":"Silva","year":"2009","journal-title":"Brazil Ciencia Rural"},{"key":"S003118202100175X_ref30","unstructured":"SAS Institute (2006) SAS user's guide: estatistics."},{"key":"S003118202100175X_ref7","unstructured":"Brener, Z (1961) Contribui\u00e7\u00e3o ao estudo da terap\u00eautica experimental da Doen\u00e7a de Chagas. 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