{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T12:05:39Z","timestamp":1780488339098,"version":"3.54.1"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"8","license":[{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Schistosoma mansoni<\/jats:italic> is the main causative agent of intestinal schistosomiasis which affects millions of people worldwide. At the larval stage, miracidia are released into bodies of water where they utilize their motility to successfully infect their intermediate host, snails. Here, we revisit the motility and survival of <jats:italic>S. mansoni<\/jats:italic> miracidia throughout its life span. Briefly, miracidia motility was monitored at 30-min and 60-min intervals under the presence\/absence of natural\/artificial light. Based on a subjective evaluation of activity, body shape and transparency, 6 categories of miracidia activity were established from its fully active stage to its immobile larva stage. The estimated life span of miracidia was 5.8 and 3.5 h in the experiments with 60-min and 30-min observation intervals, respectively. Death was defined by an absence of cilia and body movement. When mobility was used as a proxy for infectivity, infective miracidia were detected at 2.5 and 4.5 h, respectively. The present miracidia motility and survival re-evaluation supports parameters optimization for computational modelling of schistosomiasis transmission dynamics. Target control interventions, especially at late stages next to transmission interruption, may greatly benefit from improved modelling studies.<\/jats:p>","DOI":"10.1017\/s0031182022000579","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T07:15:14Z","timestamp":1652685314000},"page":"1078-1084","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["<i>Schistosoma mansoni<\/i> miracidia: revisiting motility and survival parameters for improved computational modelling"],"prefix":"10.1017","volume":"149","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3354-4181","authenticated-orcid":false,"given":"Renata Perotto","family":"de Souza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa Fey","family":"Pascoal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas Nogueira","family":"Vilches","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9lio Radke","family":"Bittencourt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Roberta Pinto","family":"Utz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2725-0061","authenticated-orcid":false,"given":"Carlos","family":"Graeff-Teixeira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,5,16]]},"reference":[{"key":"S0031182022000579_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(84)90037-7"},{"key":"S0031182022000579_ref14","doi-asserted-by":"publisher","DOI":"10.2307\/3280200"},{"key":"S0031182022000579_ref13","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00007288"},{"key":"S0031182022000579_ref3","first-page":"987","article-title":"Incidence des facteurs externes sur la long\u00e9vit\u00e9 et la vitalit\u00e9 des miracidiums de Schistosoma mansoni","volume":"56","author":"Benex","year":"1963","journal-title":"Bulletin de la Soci\u00e9t\u00e9 de Pathologie Exotique"},{"key":"S0031182022000579_ref4","doi-asserted-by":"publisher","DOI":"10.2307\/3277073"},{"key":"S0031182022000579_ref18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006948"},{"key":"S0031182022000579_ref19","volume-title":"Global Health Estimates 2016: Deaths by Cause, Age, Sex, by Country and by Region, 2000\u20132016","year":"2018"},{"key":"S0031182022000579_ref5","doi-asserted-by":"publisher","DOI":"10.2307\/3279348"},{"key":"S0031182022000579_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(54)90046-6"},{"key":"S0031182022000579_ref17","doi-asserted-by":"publisher","DOI":"10.1080\/00034983.1964.11686267"},{"key":"S0031182022000579_ref9","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1948.s1-28.645"},{"key":"S0031182022000579_ref10","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000051878"},{"key":"S0031182022000579_ref15","doi-asserted-by":"publisher","DOI":"10.2307\/3281558"},{"key":"S0031182022000579_ref7","doi-asserted-by":"publisher","DOI":"10.1890\/02-4035"},{"key":"S0031182022000579_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2019.12.003"},{"key":"S0031182022000579_ref11","doi-asserted-by":"publisher","DOI":"10.2307\/3278950"},{"key":"S0031182022000579_ref1","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000055323"},{"key":"S0031182022000579_ref8","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00005411"},{"key":"S0031182022000579_ref20","volume-title":"Ending the Neglect to Attain the Sustainable Development Goals: A Global Strategy on Water, Sanitation and Hygiene to Combat Neglected Tropical Diseases, 2021\u20132030","year":"2021"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182022000579","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,20]],"date-time":"2022-07-20T09:36:36Z","timestamp":1658309796000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182022000579\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,16]]},"references-count":19,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["S0031182022000579"],"URL":"https:\/\/doi.org\/10.1017\/s0031182022000579","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,16]]},"assertion":[{"value":"Copyright \u00a9 The Author(s), 2022. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}