{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:40:47Z","timestamp":1791312047513,"version":"4.3.1"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T00:00:00Z","timestamp":1661299200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"funder":[{"name":"Talents of the Central Plains Thousand Talents Program","award":["19CZ0122"],"award-info":[{"award-number":["19CZ0122"]}]},{"name":"NSFC-Henan Joint Fund Key Project","award":["U1904203"],"award-info":[{"award-number":["U1904203"]}]}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Cryptosporidium<\/jats:italic> spp. are important pathogens with some species causing diarrhoea in humans and animals. Sheep are one of the most common potential hosts for various <jats:italic>Cryptosporidium<\/jats:italic> spp. The prevalence of <jats:italic>Cryptosporidium<\/jats:italic> in sheep globally was evaluated from published information including molecular data via meta-analysis. In total, 126 datasets from 41 countries were included for final quantitative analysis. Sheep aged &lt;3 months had a significantly higher prevalence (27.8%; 3284\/11 938) than those at the age of 3\u201312 and &gt;12 months. The prevalence of <jats:italic>Cryptosporidium<\/jats:italic> in sheep with diarrhoea of 35.4% (844\/1915) was higher than in sheep that did not show diarrhoea (11.3%; 176\/1691). Fourteen <jats:italic>Cryptosporidium<\/jats:italic> species\/genotypes were detected in sheep globally. The proportion of subgenotype family XIIa of <jats:italic>Cryptosporidium ubiquitum<\/jats:italic> was 90.0% (216\/240); the proportions of subgenotypes IIdA20G1 and IIaA15G2R1 of <jats:italic>Cryptosporidium parvum<\/jats:italic> were 15.4% (62\/402) and 19.7% (79\/402). The results indicate that <jats:italic>C. parvum<\/jats:italic> is the dominant species in Europe while <jats:italic>Cryptosporidium xiaoi<\/jats:italic> is the dominant species in Oceania, Asia and Africa and <jats:italic>C. ubiquitum<\/jats:italic> is the dominant species in North America and South America. Subgenotype family IIa of <jats:italic>C. parvum<\/jats:italic> is particularly widespread among sheep worldwide. The results highlight the role of sheep as a reservoir host for zoonotic cryptosporidia and the need for further study of prevalence, transmission and control of this pathogen in sheep.<\/jats:p>","DOI":"10.1017\/s0031182022001196","type":"journal-article","created":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T08:15:08Z","timestamp":1661328908000},"page":"1652-1665","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":31,"title":["The global prevalence of <i>Cryptosporidium<\/i> in sheep: a systematic review and meta-analysis"],"prefix":"10.1017","volume":"149","author":[{"given":"Yuancai","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huikai","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianying","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junqiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9310-1975","authenticated-orcid":false,"given":"Longxian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,8,24]]},"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182022001196","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T00:02:32Z","timestamp":1682294552000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182022001196\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,24]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S0031182022001196"],"URL":"https:\/\/doi.org\/10.1017\/s0031182022001196","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,24]]},"assertion":[{"value":"Copyright \u00a9 The Author(s), 2022. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}