{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T01:16:09Z","timestamp":1788311769284,"version":"build-2803163510"},"reference-count":49,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T00:00:00Z","timestamp":1671408000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Taeniasis and cysticercosis, which are caused by <jats:italic>Taenia saginata<\/jats:italic>, <jats:italic>Taenia solium<\/jats:italic> and <jats:italic>Taenia asiatica<\/jats:italic>, are zoonotic parasitic infections with a significant disease burden worldwide. There is consensus amongst experts that <jats:italic>T. saginata<\/jats:italic> is a common tapeworm that causes taeniasis in humans as opposed to cysticercosis. This case study of a middle-aged Tibetan man conducted in 2021 challenges the prevailing notion that <jats:italic>T. saginata<\/jats:italic> exclusively causes taeniasis and not cysticercosis by documenting symptoms and laboratory studies related to both taeniasis and multiple cysticercosis. The patient's medical record with the symptoms of taeniasis and cysticercosis was reviewed, and the tapeworm's proglottids and cyst were identified from the patient by morphological evaluation, DNA amplification and sequencing. The patient frequently experienced severe headaches and vomiting. Both routine blood screenings and testing for antibodies against the most common parasites were normal. After anthelmintic treatment, an adult tapeworm was found in feces, and medical imaging examinations suggested multiple focal nodules in the brain and muscles of the patient. The morphological and molecular diagnosis of the proglottids revealed the Cestoda was <jats:italic>T. saginata.<\/jats:italic> Despite the challenges presented by the cyst's morphology, the molecular analysis suggested that it was most likely <jats:italic>T. saginata<\/jats:italic>. This case study suggests that <jats:italic>T. saginata<\/jats:italic> infection in humans has the potential to cause human cysticercosis. However, such a conclusion needs to be vetted by accurate genome-wide analysis in patients with <jats:italic>T. saginata<\/jats:italic> taeniasis associated with cysts. Such studies shall provide new insights into the pathogenicity of <jats:italic>T. saginata<\/jats:italic>.<\/jats:p>","DOI":"10.1017\/s003118202200169x","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T04:25:43Z","timestamp":1671423943000},"page":"240-247","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":3,"title":["A rare case of human taeniasis caused by <i>Taenia saginata<\/i> with species undetermined cysticercosis"],"prefix":"10.1017","volume":"150","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4974-5743","authenticated-orcid":false,"given":"Jie","family":"Hou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weilin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunlei","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0302-3278","authenticated-orcid":false,"given":"Ying","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junyan","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,12,19]]},"reference":[{"key":"S003118202200169X_ref19","doi-asserted-by":"publisher","DOI":"10.1017\/S0022149X00020964"},{"key":"S003118202200169X_ref42","first-page":"555","article-title":"Ein fall von cysticercus bovis im unterhautgewebe des Menschen","volume":"304","author":"Tanasescu","year":"1939","journal-title":"Virchows Archiv f\u00fcr Pathologische Anatomie und Physiologie und f\u00fcr klinische Medizin"},{"key":"S003118202200169X_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(92)90109-W"},{"key":"S003118202200169X_ref14","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-018-2646-6"},{"key":"S003118202200169X_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2018.07.003"},{"key":"S003118202200169X_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-55512-8.00130-7"},{"key":"S003118202200169X_ref1","first-page":"530","volume-title":"Principles of Cestology","volume":"IV","author":"Abuladze","year":"1964"},{"key":"S003118202200169X_ref20","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.2.737-744.2000"},{"key":"S003118202200169X_ref18","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00085-19"},{"key":"S003118202200169X_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14965-3"},{"key":"S003118202200169X_ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14117-7"},{"key":"S003118202200169X_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2004.03.013"},{"key":"S003118202200169X_ref22","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2002.2218"},{"key":"S003118202200169X_ref31","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005743"},{"key":"S003118202200169X_ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2009.10.007"},{"key":"S003118202200169X_ref24","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-021-04589-6"},{"key":"S003118202200169X_ref37","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(08)60176-1"},{"key":"S003118202200169X_ref36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004316"},{"key":"S003118202200169X_ref2","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-7-45"},{"key":"S003118202200169X_ref29","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0199609"},{"key":"S003118202200169X_ref13","first-page":"66","article-title":"Occurrence of bovine cysticercosis in two regions of the state of Tocantins-Brazil and the importance of pathogen identification","volume":"8","author":"Figueiredo","year":"2019","journal-title":"Pathogens (Basel, Switzerland)"},{"key":"S003118202200169X_ref43","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02171-15"},{"key":"S003118202200169X_ref44","doi-asserted-by":"publisher","DOI":"10.1007\/s004360050638"},{"key":"S003118202200169X_ref46","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2012.01.005"},{"key":"S003118202200169X_ref27","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkn201"},{"key":"S003118202200169X_ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2007.04.001"},{"key":"S003118202200169X_ref28","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2019.0446"},{"key":"S003118202200169X_ref40","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2015.12.010"},{"key":"S003118202200169X_ref49","doi-asserted-by":"publisher","DOI":"10.1645\/13-224.1"},{"key":"S003118202200169X_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2016.11.045"},{"key":"S003118202200169X_ref38","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.12089"},{"key":"S003118202200169X_ref15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-0998.2011.03110.x"},{"key":"S003118202200169X_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/bs.apar.2019.12.004"},{"key":"S003118202200169X_ref6","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1994.50.1.TM0500010033"},{"key":"S003118202200169X_ref9","unstructured":"De Rivas, D (1937) Cysticercus bovis in man. In Papers on helminthology published in communication of the 30 year jubileum of K. J. Skriabin."},{"key":"S003118202200169X_ref5","first-page":"1052","article-title":"La Taenia suginuta puede producir cysticercus bovis en el hombre?","volume":"43","author":"Bacigalupo JADAB","year":"1956","journal-title":"Prensa Medica Argentina"},{"key":"S003118202200169X_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2008.10.014"},{"key":"S003118202200169X_ref4","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1117639"},{"key":"S003118202200169X_ref45","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms9102006"},{"key":"S003118202200169X_ref48","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.2.548-553.2004"},{"key":"S003118202200169X_ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-020-04095-1"},{"key":"S003118202200169X_ref34","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4894(03)00111-5"},{"key":"S003118202200169X_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.tree.2019.12.003"},{"key":"S003118202200169X_ref33","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01573-08"},{"key":"S003118202200169X_ref39","doi-asserted-by":"publisher","DOI":"10.1016\/bs.apar.2020.04.005"},{"key":"S003118202200169X_ref41","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-015-4314-5"},{"key":"S003118202200169X_ref30","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.20-0782"},{"key":"S003118202200169X_ref47","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.10.3818-3821.2002"},{"key":"S003118202200169X_ref32","first-page":"3040","article-title":"Cisticercosis humana en la Republica Argentina. Estudio de ma nueva observacibn","volume":"37","author":"Niiio","year":"1950","journal-title":"Prensa Medica Argentina"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S003118202200169X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,21]],"date-time":"2023-07-21T02:45:27Z","timestamp":1689907527000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S003118202200169X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,19]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S003118202200169X"],"URL":"https:\/\/doi.org\/10.1017\/s003118202200169x","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,19]]},"assertion":[{"value":"Copyright \u00a9 The Author(s), 2022. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}