{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T13:27:47Z","timestamp":1778074067657,"version":"3.51.4"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T00:00:00Z","timestamp":1696464000000},"content-version":"unspecified","delay-in-days":34,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Optical microscopy is the gold standard technique used to confirm the diagnosis of scabies. Multiple diagnostic features of the pathogen <jats:italic>Sarcoptes scabiei<\/jats:italic> var. <jats:italic>hominis<\/jats:italic> (<jats:italic>S. scabiei<\/jats:italic>) can be identified under a microscope and classified into 3 categories: mites, eggs and fecal pellets. However, mite and eggshell fragments can also be observed, which have been ignored in the 2020 International Alliance for the Control of Scabies (IACS) Criteria and by most researchers. In this study, we propose a novel morphological classification method that classifies multiple diagnostic features into 5 categories and 7 subcategories. Our results revealed that 65.2% (1893 of 2896) of the positive cases were confirmed through the identification of mites, eggs or fecal pellets, whereas up to 34.6% (1003 of 2896) of the positive cases were confirmed through the identification of mite or eggshell fragments. Therefore, the important diagnostic values of mite and eggshell fragments should be emphasized. Importantly, for the first time, mite and eggshell fragments were classified into 7 subcategories, some of which are easily ignored or confused with contaminating artefacts. We believe that this novel morphological classification method will be beneficial for operator training in interpreting slides and in improving the 2020 IACS Criteria.<\/jats:p>","DOI":"10.1017\/s0031182023000938","type":"journal-article","created":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T10:28:15Z","timestamp":1696501695000},"page":"1070-1075","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":5,"title":["Optical microscopic study on a novel morphological classification method of multiple diagnostic features of <i>Sarcoptes scabiei<\/i> var. <i>hominis<\/i>"],"prefix":"10.1017","volume":"150","author":[{"given":"Wanchen","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoli","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4600-2813","authenticated-orcid":false,"given":"Lin","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongfeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaliu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianjun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2023,10,5]]},"reference":[{"key":"S0031182023000938_ref2","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-017-2234-1"},{"key":"S0031182023000938_ref18","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00042-06"},{"key":"S0031182023000938_ref13","doi-asserted-by":"publisher","DOI":"10.1111\/ced.14794"},{"key":"S0031182023000938_ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1985.tb00436.x"},{"key":"S0031182023000938_ref1","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.2017.01.160190"},{"key":"S0031182023000938_ref12","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00480-19"},{"key":"S0031182023000938_ref5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006549"},{"key":"S0031182023000938_ref10","first-page":"33","article-title":"Scabies: a neglected global disease","volume":"16","author":"Leung","year":"2020","journal-title":"Current Pediatric Reviews"},{"key":"S0031182023000938_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.05.109"},{"key":"S0031182023000938_ref17","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.51"},{"key":"S0031182023000938_ref19","doi-asserted-by":"publisher","DOI":"10.4274\/tpd.galenos.2021.6874"},{"key":"S0031182023000938_ref6","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18943"},{"key":"S0031182023000938_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4017(87)90104-X"},{"key":"S0031182023000938_ref8","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02350-16"},{"key":"S0031182023000938_ref3","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13746"},{"key":"S0031182023000938_ref9","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-019-7085-6"},{"key":"S0031182023000938_ref4","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-3468"},{"key":"S0031182023000938_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.mbs.2018.08.007"},{"key":"S0031182023000938_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31678-6"}],"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182023000938","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T13:06:41Z","timestamp":1700831201000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182023000938\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":19,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["S0031182023000938"],"URL":"https:\/\/doi.org\/10.1017\/s0031182023000938","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Copyright \u00a9 The Author(s), 2023. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}