{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T17:37:48Z","timestamp":1792431468346,"version":"4.5.0"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Parasitology"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Haemonchus contortus<\/jats:italic>\n                    , a highly pathogenic gastrointestinal nematode, significantly impacts small ruminant production, causing substantial economic losses in sheep and goat farming. This study examined the genetic diversity and population structure of 171\n                    <jats:italic>H. contortus<\/jats:italic>\n                    isolates collected from the abomasa of sheep slaughtered across 8 distinct regions in Xinjiang, China. Using sequence analysis, phylogenetic reconstruction and population genetic analyses of the mitochondrial\n                    <jats:italic>nad4<\/jats:italic>\n                    gene, we identified 163 haplotypes, with haplotype diversity ranging from 0.995 to 1.000 and nucleotide diversity from 0.02007 to 0.03145. The Tacheng population displayed the highest nucleotide diversity. Analysis of molecular variance revealed that 91.83% of genetic variation occurred within populations, with minimal differentiation among them (Fst:\u00a0\u22120.01296 to 0.04274). Neutrality tests (Tajima\u2019s D and Fu\u2019s Fs) indicated no recent population bottlenecks. Phylogenetic and haplotype network analyses showed no distinct geographic clustering, suggesting extensive gene flow, likely facilitated by host movement. These findings provide critical insights into the genetic structure of\n                    <jats:italic>H. contortus<\/jats:italic>\n                    in Xinjiang, informing strategies for managing anthelmintic resistance and controlling this economically significant parasite.\n                  <\/jats:p>","DOI":"10.1017\/s0031182025101352","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T02:11:02Z","timestamp":1766110262000},"page":"1-10","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Genetic diversity and population structure of\n                    <i>Haemonchus contortus<\/i>\n                    isolates from sheep across Xinjiang, China"],"prefix":"10.1017","author":[{"given":"Waresi","family":"Tuersong","sequence":"first","affiliation":[{"name":"Xinjiang Agricultural University"},{"name":"Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous"},{"name":"Veterinary Medicine Postdoctoral Research Station of Xinjiang Agricultural University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6328-1249","authenticated-orcid":false,"given":"Reyilanmu","family":"Tuerhong","sequence":"additional","affiliation":[{"name":"Xinjiang Agricultural University"},{"name":"Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abudusaimaiti","family":"Tuoheti","sequence":"additional","affiliation":[{"name":"Xinjiang Agricultural University"},{"name":"Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ailixire","family":"Maimaiti","sequence":"additional","affiliation":[{"name":"Veterinary Research Institute, Xinjiang Academy of Animal Husbandry"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilare","family":"Xuekelaiti","sequence":"additional","affiliation":[{"name":"Xinjiang Agricultural University"},{"name":"Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianxi","family":"Xin","sequence":"additional","affiliation":[{"name":"Xinjiang Agricultural University"},{"name":"Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aiheda","family":"Aideli","sequence":"additional","affiliation":[{"name":"Xinjiang Agricultural University"},{"name":"Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Xiao","sequence":"additional","affiliation":[{"name":"Xinjiang Agricultural University"},{"name":"Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Hu","sequence":"additional","affiliation":[{"name":"Huazhong Agricultural University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saifuding","family":"Abula","sequence":"additional","affiliation":[{"name":"Xinjiang Agricultural University"},{"name":"Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chahan","family":"Bayin","sequence":"additional","affiliation":[{"name":"Xinjiang Agricultural University"},{"name":"Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingyong","family":"Guo","sequence":"additional","affiliation":[{"name":"Xinjiang Agricultural University"},{"name":"Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Xinjiang Agricultural University"},{"name":"Xinjiang Key Laboratory of New Drug Research and Development for Herbivorous"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,12,19]]},"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182025101352","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T06:53:28Z","timestamp":1766472808000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182025101352\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,19]]},"references-count":0,"alternative-id":["S0031182025101352"],"URL":"https:\/\/doi.org\/10.1017\/s0031182025101352","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,19]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. Published by Cambridge University Press.","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}