{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T04:05:17Z","timestamp":1758945917993},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[1997,9,1]],"date-time":"1997-09-01T00:00:00Z","timestamp":873072000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1997,9]]},"abstract":"<jats:p>Interactions between adult <jats:italic>Hymenolepis diminuta<\/jats:italic> and \nrat C-reactive protein (CRP) were investigated <jats:italic>in vivo<\/jats:italic> and <jats:italic>in \nvitro<\/jats:italic>. Using an ELISA technique, serum levels of CRP were monitored \nin rats infected with 100 cysticercoids. Although \ninfection increased the level of this protein in the early stages of \nparasitization, the increase was not significant until 35 \ndays post-infection (p.i.). Secondary infections did not enhance the response. \nWhen <jats:italic>H. diminuta<\/jats:italic> was cultured in the \npresence of CRP, reduced worm motility and opaque areas were observed and \nelectron microscopical studies revealed \nshedding of microtriches and lysis of the tegument. Initially, damage was \nrestricted to the strobila which correlated with \nthe regional distribution of phosphorylcholine as visualized using \nimmunofluorescence.<\/jats:p>","DOI":"10.1017\/s0031182097001418","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:30:22Z","timestamp":1027762222000},"page":"297-302","source":"Crossref","is-referenced-by-count":10,"title":["Interactions between rat C-reactive protein and adult \n<i>Hymenolepis diminuta<\/i>"],"prefix":"10.1017","volume":"115","author":[{"given":"K.","family":"TAYLOR","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"HOOLE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[1997,9,1]]},"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182097001418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,11]],"date-time":"2019-05-11T16:22:33Z","timestamp":1557591753000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182097001418\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,9]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,9]]}},"alternative-id":["S0031182097001418"],"URL":"https:\/\/doi.org\/10.1017\/s0031182097001418","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,9]]}}}