{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T01:47:36Z","timestamp":1790905656490,"version":"4.1.0"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[1997,11,1]],"date-time":"1997-11-01T00:00:00Z","timestamp":878342400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1997,11]]},"abstract":"<jats:p>Using surface immunofluorescence isolate-specific antigens \nwere detected on the membrane of erythrocytes infected with \n<jats:italic>Babesia<\/jats:italic> parasites. In addition, the strains reacted differently \nwith Plasmagel in that the European isolate (<jats:italic>B.c. canis<\/jats:italic>) could \nbe purified on Plasmagel effectively, whereas infected erythrocytes of\n the \nSouth-African isolate (<jats:italic>B.c. rossi<\/jats:italic>) could not. \nExperimental infection of dogs with <jats:italic>Babesia canis<\/jats:italic> isolates from \ngeographically different areas revealed different pathology. \nThe European isolate obtained from France exhibited transient parasitaemia,\n usually \nbelow 1%, associated with low PCV \nvalues and congestion of internal organs. Clinical disease was correlated\n with \nan effect on the coagulation system, and not \nwith peripheral parasitaemia. Infection of dogs with South-African-derived \nisolate induced high parasitaemia usually \nmuch higher than 1%, which required chemotherapeutic treatment. In these\n animals \nclinical disease was correlated with \nperipheral parasitaemia and not with parameters of the coagulation system.\n The \nresults show that the etiology of disease \ncaused by these isolates of <jats:italic>B.c. canis<\/jats:italic> and <jats:italic>B.c. rossi<\/jats:italic> \nis different. This might have implications for the development of \nvaccines against these infections.<\/jats:p>","DOI":"10.1017\/s0031182097001686","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:30:22Z","timestamp":1027762222000},"page":"485-493","source":"Crossref","is-referenced-by-count":75,"title":["Different <i>Babesia canis<\/i> isolates, different diseases"],"prefix":"10.1017","volume":"115","author":[{"given":"TH. P. M.","family":"SCHETTERS","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"MOUBRI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"PR\u00c9CIGOUT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"KLEUSKENS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. C.","family":"SCHOLTES","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"GORENFLOT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[1997,11,1]]},"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182097001686","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,11]],"date-time":"2019-05-11T15:59:35Z","timestamp":1557590375000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182097001686\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,11]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1997,11]]}},"alternative-id":["S0031182097001686"],"URL":"https:\/\/doi.org\/10.1017\/s0031182097001686","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,11]]}}}