{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T07:40:44Z","timestamp":1770622844701,"version":"3.49.0"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[1998,10,1]],"date-time":"1998-10-01T00:00:00Z","timestamp":907200000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1998,10]]},"abstract":"<jats:p>It has recently been shown using genetic markers that <jats:italic>Ascaris<\/jats:italic>\n \nin humans and pigs in Central America comprise \nreproductively isolated populations. We present a similar analysis for\n a \nregion of China in which close association between \npigs and humans has been the norm for thousands of years, and agricultural\n \npractices will result in frequent exposure to \neggs from both sources. DNA fragments from selected regions of mitochondrial\n \nand ribosomal DNA were amplified by \nPCR and allelic forms identified following digestion with a panel of \nrestriction enzymes, using DNA from a total of 115 \nindividual worms from both people and pigs from 2 neighbouring villages.\n \nSignificant frequency differences in both \nmtDNA haplotypes and the rDNA spacer were found between the 2 host-associated\n \npopulations, indicating that they \nrepresented reproductively isolated populations. Mitochondrial haplotype\n \nfrequencies were different from those observed \nin Guatemala and also from other Asian <jats:italic>Ascaris<\/jats:italic> populations, \nsuggesting low levels of gene flow between populations. \nHowever, we found no evidence for significant heterogeneity in the \ngenetic composition of <jats:italic>Ascaris<\/jats:italic> infrapopulations in \neither humans or pigs, possibly indicative of agricultural practices \nin China which have resulted in a random distribution \nof alleles within the parasite populations.<\/jats:p>","DOI":"10.1017\/s0031182098003102","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T13:30:22Z","timestamp":1027776622000},"page":"355-361","source":"Crossref","is-referenced-by-count":62,"title":["Genetic variation in sympatric <i>Ascaris<\/i> populations from \nhumans and pigs in China"],"prefix":"10.1017","volume":"117","author":[{"given":"WEIDONG","family":"PENG","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. J. C.","family":"ANDERSON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"XIANMIN","family":"ZHOU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. W.","family":"KENNEDY","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[1998,10,1]]},"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182098003102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,10]],"date-time":"2019-05-10T20:07:35Z","timestamp":1557518855000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182098003102\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,10]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1998,10]]}},"alternative-id":["S0031182098003102"],"URL":"https:\/\/doi.org\/10.1017\/s0031182098003102","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,10]]}}}