{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T17:16:58Z","timestamp":1773422218915,"version":"3.50.1"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[1999,2,1]],"date-time":"1999-02-01T00:00:00Z","timestamp":917827200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1999,2]]},"abstract":"<jats:p>To examine levels of heat shock proteins (HSPs) in host responses\n to helminth infection, rats were infected with <jats:italic>Trichinella \nspiralis<\/jats:italic>. The kinetics of HSP25, HSP60, HSP70 and HSP90 production\n in the liver and muscle of infected rats was \ncompared with that of non-infected controls. HSPs were detected using electrophoretic\n analysis of fixed amounts of \nproteins (0\u00b702 mg) and then blotting and incubation of membranes\n with polyclonal anti-HSP25 antibody, or monoclonal \nantibody against HSP60, or HSP70 or HSP90. Quantitation of blotted separated\n polypeptides reactive with the specific \nanti-HSP antibodies was achieved using an image analyser. Enhancement of\n HSP25 production was observed in the liver \nof infected rats, whereas muscle from the same rats exhibited enhanced\n production of HSP25 and HSP60 one day after \ninfection only. These data indicate that HSPs levels can be used successfully\n to measure stress injury brought about by \nhelminth infection in organs and tissues of the host.<\/jats:p>","DOI":"10.1017\/s0031182098003692","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T13:30:22Z","timestamp":1027776622000},"page":"201-209","source":"Crossref","is-referenced-by-count":22,"title":["Influence of parasitization by <i>Trichinella spiralis<\/i> on the\n \nlevels of heat shock proteins in rat liver and muscle"],"prefix":"10.1017","volume":"118","author":[{"given":"J.","family":"MARTINEZ","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"PEREZ SERRANO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. E.","family":"BERNADINA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"RODRIGUEZ-CAABEIRO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[1999,2,1]]},"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182098003692","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T19:48:10Z","timestamp":1554148090000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182098003692\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,2]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1999,2]]}},"alternative-id":["S0031182098003692"],"URL":"https:\/\/doi.org\/10.1017\/s0031182098003692","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,2]]}}}