{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T18:53:33Z","timestamp":1697568813253},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[1999,3,1]],"date-time":"1999-03-01T00:00:00Z","timestamp":920246400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1999,3]]},"abstract":"<jats:p><jats:italic>Oesophagostomum bifurcum<\/jats:italic>, as well as hookworm infections\n are hyperendemic among humans in northern Togo and Ghana. \nFor parasite-specific diagnosis a coproculture is obligatory, because only\n the infective larvae, and not the eggs, can be \ndistinguished morphologically. The sensitivity of duplicate coprocultures\n from a single stool sample was found to be above \n90% in comparison to a gold standard of 10 coprocultures made from a single\n stool specimen. Prevalence of infection with \n<jats:italic>O. bifurcum<\/jats:italic> and hookworm further increased with the number of\n coprocultures made from each individual stool. \nNotwithstanding the high sensitivity, intensity of infection per individual\n varied considerably from day-to-day and the \nnumber of larvae found in different samples out of 1 stool also varied\n highly, both showing a heterogeneous distribution. \nSurprisingly, daily fluctuation and within-specimen variation could not\n be differentiated from each other, probably \nbecause of the variation created by the coproculture technique. To estimate\n the intensity of infection, it is sufficient to \nmake repeated coprocultures from only 1 individual stool sample. Laborious\n collection of stool samples on subsequent \ndays does not give better estimates of the individual infection status.<\/jats:p>","DOI":"10.1017\/s0031182098003849","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:30:22Z","timestamp":1027762222000},"page":"283-288","source":"Crossref","is-referenced-by-count":14,"title":["Diagnosis of <i>Oesophagostomum bifurcum<\/i> and hookworm \ninfection in humans: day-to-day and within-specimen \nvariation of larval counts"],"prefix":"10.1017","volume":"118","author":[{"given":"D. S. S.","family":"PIT","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"DE GRAAF","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"SNOEK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. J.","family":"DE VLAS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. M.","family":"BAETA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"POLDERMAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[1999,3,1]]},"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182098003849","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T15:18:43Z","timestamp":1554131923000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182098003849\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,3]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1999,3]]}},"alternative-id":["S0031182098003849"],"URL":"https:\/\/doi.org\/10.1017\/s0031182098003849","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,3]]}}}