{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T08:50:14Z","timestamp":1762159814250},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[1999,4,1]],"date-time":"1999-04-01T00:00:00Z","timestamp":922924800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1999,4]]},"abstract":"<jats:p>Nematode surface coat (SC) proteins and excreted\u2013secreted\n products (E\u2013S) are likely to play important roles in the \nhost\u2013parasite interaction and considerable similarities can be found\n in SC proteins and E\u2013S products from certain plant \nand animal parasitic nematodes. Monoclonal antibodies raised to E\u2013S\n products of plant-parasitic nematodes were shown \nto cross-react with E\u2013S products and the surface coats of the animal\n parasites <jats:italic>Trichinella spiralis<\/jats:italic> and <jats:italic>Haemonchus contortus<\/jats:italic>.\n \nMost of the antibodies recognized carbohydrate epitopes but the activity\n of 2 MAbs (IACR\u2013CCNj.2a.15 and IACR-Misec.8D.3) \nwhich recognized proteic epitopes in these nematodes were further characterized.\n Antibody 2a.15 recognized \nthe SC and oral exudate of <jats:italic>Meloidogyne incognita<\/jats:italic>, <jats:italic>T. spiralis<\/jats:italic>\n and <jats:italic>H. contortus<\/jats:italic>. This antigen was also \nimmunolocalized in the lining of the oesophagus and gut and in the exudate\n present during ecdysis of <jats:italic>H. contortus<\/jats:italic> L<jats:sub>3<\/jats:sub>. Antibody\n \n8D.3 reacted with the SC of these nematodes on cryosections but on live\n nematodes the immunofluorescence was very \npatchy and was shed from the nematode SC.<\/jats:p>","DOI":"10.1017\/s0031182098003941","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:30:22Z","timestamp":1027762222000},"page":"397-405","source":"Crossref","is-referenced-by-count":16,"title":["Identification and characterization of excreted\u2013secreted \nproducts and surface coat antigens of animal and plant-parasitic nematodes"],"prefix":"10.1017","volume":"118","author":[{"given":"M. E. LOPEZ","family":"DE MENDOZA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. H. C.","family":"CURTIS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"GOWEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[1999,4,1]]},"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182098003941","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,7]],"date-time":"2019-04-07T16:25:49Z","timestamp":1554654349000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182098003941\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,4]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1999,4]]}},"alternative-id":["S0031182098003941"],"URL":"https:\/\/doi.org\/10.1017\/s0031182098003941","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,4]]}}}