{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T02:55:23Z","timestamp":1782183323317,"version":"3.54.5"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2009,10,16]],"date-time":"2009-10-16T00:00:00Z","timestamp":1255651200000},"content-version":"unspecified","delay-in-days":3607,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1999,12]]},"abstract":"<jats:p>The development of nasal avian schistosomes of the genus <jats:italic>Trichobilharzia<\/jats:italic> in their final host is poorly known. Therefore, \nan experimental infection of ducklings (<jats:italic>Anas platyrhynchos f. dom<\/jats:italic>.) by <jats:italic>T. regenti<\/jats:italic> was performed. The infection resulted \nin leg paralysis and orientation\/balance disorders of birds. The examination of the duck's spinal cord and brain confirmed \nthe presence of developing parasites in pre-patent as well as patent periods. The absence of the worms in other tissues \nstrongly supports our hypothesis that the parasite migrates through the central nervous system (CNS) to its final location \nin bird nasal mucosa. The injury level is probably dependent on number of parasites as well as yet unknown host factors. \nThe affinity to the CNS seems to be high; also by exposure of experimental animals to low cercarial doses the growing \nworms in the CNS were found. In addition to the generally accepted view that bird schistosomes may cause cercarial \ndermatitis of mammals (including man), there is evidence of a partial development of <jats:italic>T. regenti<\/jats:italic> in mouse CNS; in certain \ncases leg paralysis was also recorded. Therefore, the pathogenesis spectrum caused by bird schistosomes in birds\/mammals \nneeds to be reconsidered.<\/jats:p>","DOI":"10.1017\/s0031182099005132","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:30:22Z","timestamp":1027762222000},"page":"577-581","source":"Crossref","is-referenced-by-count":69,"title":["<i>Trichobilharzia regenti<\/i>, a pathogen of the avian and \nmammalian central nervous systems"],"prefix":"10.1017","volume":"119","author":[{"given":"P.","family":"HOR\u00c1K","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"DVO\u0158\u00c1K","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"KOL\u00c1\u0158OV\u00c1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"TREFIL","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2009,10,16]]},"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182099005132","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T15:47:04Z","timestamp":1557416824000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182099005132\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,12]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1999,12]]}},"alternative-id":["S0031182099005132"],"URL":"https:\/\/doi.org\/10.1017\/s0031182099005132","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,12]]}}}