{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T11:49:48Z","timestamp":1726919388729},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2000,2,1]],"date-time":"2000-02-01T00:00:00Z","timestamp":949363200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[2000,2]]},"abstract":"<jats:p>In this paper we address the question of detecting immunity to helminth infections from patterns of infection in endemic \ncommunities. We use stochastic simulations to investigate whether it would be possible to detect patterns predicted by \ntheoretical models, using typical field data. Thus, our technique is to simulate a theoretical model, to generate the data \nthat would be obtained in field surveys and then to analyse these data using methods usually employed for field data. The \ngeneral behaviour of the model, and in particular the levels of variability of egg counts predicted, show that the model \nis capturing most of the variability present in field data. However, analysis of the data in detail suggests that detection of \nimmunity patterns in real data may be very difficult even if the underlying patterns are present. Analysis of a real data \nset does show patterns consistent with acquired immunity and the implications of this are discussed.<\/jats:p>","DOI":"10.1017\/s003118209900534x","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:30:22Z","timestamp":1027762222000},"page":"161-169","source":"Crossref","is-referenced-by-count":11,"title":["Stochastic simulation and the detection of immunity to \nschistosome infections"],"prefix":"10.1017","volume":"120","author":[{"given":"M. S.","family":"CHAN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"MUTAPI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. E. J.","family":"WOOLHOUSE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. S.","family":"ISHAM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2000,2,1]]},"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S003118209900534X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T15:23:19Z","timestamp":1554218599000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S003118209900534X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,2]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2000,2]]}},"alternative-id":["S003118209900534X"],"URL":"https:\/\/doi.org\/10.1017\/s003118209900534x","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,2]]}}}