{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T11:16:44Z","timestamp":1696331804728},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2009,7,9]],"date-time":"2009-07-09T00:00:00Z","timestamp":1247097600000},"content-version":"unspecified","delay-in-days":7921,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[1987,11]]},"abstract":"<jats:title>Synopsis<\/jats:title><jats:p>Urinary excretions of arginine vasopressin (AVP), sodium, potassium, osmoles and creatinine were measured in three in-patients with bipolar manic-depressive psychosis on at least eight 24-hour periods in each affective phase. Mood and body weight were recorded twice daily. The excretion by each patient of sodium, water and osmoles was greater in mania than during depression. Comparison of electrolytes and osmoles suggested that the increase was due to increased intake of salt and water rather than of total diet. There was a fall of mean AVP excretion during mania, the magnitude of the fall being related to the increase of water throughput.<\/jats:p><jats:p>Compared with controls, AVP excretion was high and variable. It did not show the normal relationship to urine osmolality. Days with very high AVP were not associated with any characteristic feature of the other measurements; nor were they confined to any one point in the manic-depressive cycle.<\/jats:p><jats:p>AVP does not appear to play a major role in the salt and water changes characteristic of manicdepressive psychosis and we have no evidence of its having any direct relationship to mood changes. We suggest that the observed abnormalities of AVP excretion are another manifestation of the central defect of this disease.<\/jats:p>","DOI":"10.1017\/s0033291700000659","type":"journal-article","created":{"date-parts":[[2009,7,9]],"date-time":"2009-07-09T14:35:43Z","timestamp":1247150143000},"page":"861-867","source":"Crossref","is-referenced-by-count":2,"title":["Arginine vasopressin in manic-depressive psychosis"],"prefix":"10.1017","volume":"17","author":[{"given":"M. D.","family":"Penney","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. J.","family":"Levell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. P.","family":"Hullin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,7,9]]},"reference":[{"key":"S0033291700000659_ref014","first-page":"333","article-title":"The regulations of vasopressin function in health and disease","volume":"33","author":"Robertson","year":"1977","journal-title":"Recent Progress in Hormone Research"},{"key":"S0033291700000659_ref001","first-page":"585","article-title":"Ergebnisse Stoffwechselpathologischer Untersuchungen bei Psychosen. III Das Manisch-depressive Irresein","volume":"9","author":"Allers","year":"1914","journal-title":"Zeitschrift f\u00fcr die Gesamte Neurologie und Psychiatrie"},{"key":"S0033291700000659_ref007","first-page":"XXIV","article-title":"The cyclical excretion of a sodium thioglycollate-resistant antidiuretic factor by a periodic psychotic","volume":"38","author":"Goodwin","year":"1967","journal-title":"Journal of Endocrinology"},{"key":"S0033291700000659_ref004","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.39.447.19"},{"key":"S0033291700000659_ref002","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1093\/clinchem\/25.3.432","article-title":"Incorrect least-squares regression coefficients in method-comparison analysis","volume":"25","author":"Cornbleet","year":"1979","journal-title":"Clinical Chemistry"},{"key":"S0033291700000659_ref011","volume-title":"Renal Function","author":"O'Connor","year":"1962"},{"key":"S0033291700000659_ref003","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(59)90709-3"},{"key":"S0033291700000659_ref005","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)92467-4"},{"key":"S0033291700000659_ref010","doi-asserted-by":"publisher","DOI":"10.1042\/cs0630549"},{"key":"S0033291700000659_ref006","first-page":"7","article-title":"Vasopressin function in depression and mania","volume":"17","author":"Gold","year":"1981","journal-title":"Pharmacology Bulletin"},{"key":"S0033291700000659_ref008","unstructured":"Hullin R. P. (1979). Minimum effective plasma lithium levels for long-term preventive treatment of recurrent affective disorders.In: Lithium Controversies and Unresolved Issues. Proceedings of the International Lithium Conference (ed Cooper T. B. , Gershon S. , Kline N. S. and Schou M. ), pp. 333\u2013334. Excerpta Medica: Amsterdam."},{"key":"S0033291700000659_ref009","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6176.1457"},{"key":"S0033291700000659_ref012","doi-asserted-by":"publisher","DOI":"10.1042\/cs0610793"},{"key":"S0033291700000659_ref013","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700043026"},{"key":"S0033291700000659_ref015","first-page":"525","article-title":"The specificity of antisera for the radioimmunoassay of arginine-vasopressin in human plasma and urine during water loading and dehydration","volume":"51","author":"Thomas","year":"1976","journal-title":"Clinical Science and Molecular Medicine"}],"container-title":["Psychological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0033291700000659","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T11:21:58Z","timestamp":1589973718000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0033291700000659\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,11]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1987,11]]}},"alternative-id":["S0033291700000659"],"URL":"https:\/\/doi.org\/10.1017\/s0033291700000659","relation":{},"ISSN":["0033-2917","1469-8978"],"issn-type":[{"value":"0033-2917","type":"print"},{"value":"1469-8978","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,11]]}}}