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All compounds effective as antipsychotics, except sulpiride, depressed aggregation. Unmedicated schizophrenics showed aggregation responses indistinguishable from healthy controls. However, within days of treatment with either trifluoroperazine or haloperidol responses became abnormal in acutely psychotic patients. Increased responses to 5-HT and depressed responses to platelet activating factor were detected. After 4 weeks of treatment responses tended to return to normal. Aggregation responses were normal in those patients on long-term depot neuroleptics.<\/jats:p>","DOI":"10.1017\/s0033291700000672","type":"journal-article","created":{"date-parts":[[2009,7,9]],"date-time":"2009-07-09T14:35:43Z","timestamp":1247150143000},"page":"875-881","source":"Crossref","is-referenced-by-count":12,"title":["Neuroleptic effects on platelet aggregation: a study in normal volunteers and schizophrenics"],"prefix":"10.1017","volume":"17","author":[{"given":"Timothy G.","family":"Dinan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2009,7,9]]},"reference":[{"key":"S0033291700000672_ref019","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1981.tb00530.x"},{"key":"S0033291700000672_ref024","volume-title":"The Measurement and Classification of Psychiatric 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