{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T01:29:30Z","timestamp":1772846970640,"version":"3.50.1"},"reference-count":42,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2009,7,9]],"date-time":"2009-07-09T00:00:00Z","timestamp":1247097600000},"content-version":"unspecified","delay-in-days":6825,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[1990,11]]},"abstract":"<jats:title>Synopsis<\/jats:title><jats:p>Sixty surviving patients from a community-based stroke register who had CT scan evidence of a single brain lesion and neurological signs appropriate to it were interviewed three to five years following their first-ever stroke. Mood disorder (anxiety and depression), physical disability, and intellectual impairment were assessed using standardized measures. The position and volume of the brain lesion was determined from CT scans performed soon after the stroke. The prevalence of depressive disorder was lower in this sample than that reported in previous studies (DSM-IIIR major depression 8 3 %; all DSM-IIIR depressive disorders 183%). Reports by other workers for an association of depressive disorder either with left-sided brain lesions, or with anteriorly placed lesions in the left cerebral hemisphere, were not supported. Neither was there evidence of a correlation between symptom score and proximity of the lesion to the anterior pole of the left cerebral hemisphere. Psychiatric symptom scores were however greater with larger volume brain lesions. Anxiety disorders, especially agoraphobia, were relatively common (20 % if diagnosed in the presence of depressive disorder), but were not related to lesion location or volume.<\/jats:p>","DOI":"10.1017\/s0033291700036503","type":"journal-article","created":{"date-parts":[[2009,7,9]],"date-time":"2009-07-09T14:17:31Z","timestamp":1247149051000},"page":"815-828","source":"Crossref","is-referenced-by-count":107,"title":["Mood disorders in long-term survivors of stroke: associations with brain lesion location and volume"],"prefix":"10.1017","volume":"20","author":[{"given":"M.","family":"Sharpe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Hawton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"House","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Molyneux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Sandercock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Bamford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Warlow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2009,7,9]]},"reference":[{"key":"S0033291700036503_ref041","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700014264"},{"key":"S0033291700036503_ref038","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.151.2.200"},{"key":"S0033291700036503_ref035","volume-title":"Statistical Package for Social Scientists (SPSSX)","year":"1988"},{"key":"S0033291700036503_ref030","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/107.1.81"},{"key":"S0033291700036503_ref029","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.144.3.256"},{"key":"S0033291700036503_ref028","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1176\/ajp.143.10.1238","article-title":"Two year longitudinal study of post-stroke mood disorders: comparison of acute onset with delayed onset depression","volume":"143","author":"Robinson","year":"1986","journal-title":"American Journal of Psychiatry"},{"key":"S0033291700036503_ref027","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.14.5.736"},{"key":"S0033291700036503_ref026","doi-asserted-by":"publisher","DOI":"10.1038\/255332a0"},{"key":"S0033291700036503_ref019","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.143.3.266"},{"key":"S0033291700036503_ref040","volume-title":"The Measurement and Classification of Psychiatric Symptoms","author":"Wing","year":"1974"},{"key":"S0033291700036503_ref015","doi-asserted-by":"publisher","DOI":"10.1002\/gps.930020403"},{"key":"S0033291700036503_ref014","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/12.2.166"},{"key":"S0033291700036503_ref009","doi-asserted-by":"publisher","DOI":"10.3109\/03790798709166209"},{"key":"S0033291700036503_ref024","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.30.10.1090"},{"key":"S0033291700036503_ref006","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.51.11.1373"},{"key":"S0033291700036503_ref004","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.19.9.1074"},{"key":"S0033291700036503_ref002","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"1987"},{"key":"S0033291700036503_ref021","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.296.6632.1313"},{"key":"S0033291700036503_ref018","article-title":"Mood disorders in the first year after stroke","author":"House","year":"1990","journal-title":"British Journal of Psychiatry"},{"key":"S0033291700036503_ref033","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/109.3.537"},{"key":"S0033291700036503_ref010","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.154.2.195"},{"key":"S0033291700036503_ref003","unstructured":"Bamford J. (1986). The classification and natural history of acute cerebrovascular disease. M.D. thesis, Unviersity of Manchester."},{"key":"S0033291700036503_ref023","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.18.3.579"},{"key":"S0033291700036503_ref037","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/110.4.1045"},{"key":"S0033291700036503_ref012","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.40.10.1018"},{"key":"S0033291700036503_ref036","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.154.2.170"},{"key":"S0033291700036503_ref008","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.151.1.52"},{"key":"S0033291700036503_ref007","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.295.6594.379"},{"key":"S0033291700036503_ref013","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.292.6522.746"},{"key":"S0033291700036503_ref025","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.13.5.635"},{"key":"S0033291700036503_ref001","first-page":"113","article-title":"Cerebrovascular disease in the community; results of a WHO collaborative study","volume":"58","author":"Aho","year":"1980","journal-title":"WHO Bulletin"},{"key":"S0033291700036503_ref022","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1984.01790210041006"},{"key":"S0033291700036503_ref034","volume-title":"Instruction Manual for the Structured Clinical Interview for DSM-IIIR","author":"Spitzer","year":"1986"},{"key":"S0033291700036503_ref020","first-page":"61","article-title":"Functional evaluation: the Barthel Index","volume":"14","author":"Mahoney","year":"1965","journal-title":"Maryland State Medical Journal"},{"key":"S0033291700036503_ref039","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1176\/ajp.145.8.976","article-title":"Psychiatric disorder in a sample of the general population with and without chronic medical conditions","volume":"145","author":"Wells","year":"1988","journal-title":"American Journal of Psychiatry"},{"key":"S0033291700036503_ref011","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"S0033291700036503_ref017","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/113.4.1113"},{"key":"S0033291700036503_ref016","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.298.6679.991"},{"key":"S0033291700036503_ref031","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1176\/ajp.142.12.1424","article-title":"Mood disorders in left-handed stroke patients","volume":"142","author":"Robinson","year":"1985","journal-title":"American Journal of Psychiatry"},{"key":"S0033291700036503_ref032","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.18.5.837"},{"key":"S0033291700036503_ref042","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1983.tb09716.x"},{"key":"S0033291700036503_ref005","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.292.6532.1369"}],"container-title":["Psychological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0033291700036503","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,18]],"date-time":"2019-05-18T19:53:35Z","timestamp":1558209215000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0033291700036503\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,11]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1990,11]]}},"alternative-id":["S0033291700036503"],"URL":"https:\/\/doi.org\/10.1017\/s0033291700036503","relation":{},"ISSN":["0033-2917","1469-8978"],"issn-type":[{"value":"0033-2917","type":"print"},{"value":"1469-8978","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,11]]}}}