{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T18:17:31Z","timestamp":1774289851382,"version":"3.50.1"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"7","license":[{"start":{"date-parts":[[2002,10,21]],"date-time":"2002-10-21T00:00:00Z","timestamp":1035158400000},"content-version":"unspecified","delay-in-days":20,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2002,10]]},"abstract":"<jats:p><jats:bold>Background.<\/jats:bold> Childhood adversity places individuals with major depression at risk for anxiety and dysthymia co-morbidity. The goal of the present paper is to broaden this area of research by examining specificity between the type of adversity (e.g. abuse <jats:italic>versus<\/jats:italic> neglect\/indifference) and the resulting co-morbid disorder (e.g. anxiety <jats:italic>versus<\/jats:italic> dysthymia co-morbidity).<\/jats:p><jats:p><jats:bold>Method.<\/jats:bold> The volunteer sample consisted of 76 women meeting Diagnostic and Statistical Manual (DSM-IV) criteria for major depression. Of these, 28 were diagnosed with a co-morbid anxiety disorder and 21 were diagnosed with co-morbid dysthymia. Childhood physical abuse, sexual abuse, psychological abuse, antipathy and indifference were assessed using a contextual interview and rating system.<\/jats:p><jats:p><jats:bold>Results.<\/jats:bold> Severe sexual abuse and psychological abuse were significantly and preferentially associated with co-morbid anxiety, while severe physical abuse was significantly and preferentially associated with co-morbid dysthymia. Indifference and antipathy were significantly associated with both co-morbid anxiety and dysthymia. Multivariate analyses revealed that severe sexual abuse was the adverse childhood experience most strongly associated with co-morbid anxiety.<\/jats:p><jats:p><jats:bold>Conclusions.<\/jats:bold> These results suggest that particular adverse experiences in childhood do set up specific vulnerabilities to the expression of anxiety <jats:italic>versus<\/jats:italic> dysthymia co-morbidity in adulthood major depression. Cognitive mediators of these associations are discussed as avenues of future research.<\/jats:p>","DOI":"10.1017\/s0033291702006177","type":"journal-article","created":{"date-parts":[[2002,10,30]],"date-time":"2002-10-30T11:47:02Z","timestamp":1035978422000},"page":"1239-1249","source":"Crossref","is-referenced-by-count":40,"title":["Childhood adversity and anxiety <i>versus<\/i> dysthymia co-morbidity in major depression"],"prefix":"10.1017","volume":"32","author":[{"given":"KATE L.","family":"HARKNESS","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JENNIFER E.","family":"WILDES","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2002,10,21]]},"container-title":["Psychological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0033291702006177","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T00:31:37Z","timestamp":1557189097000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0033291702006177\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,10]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2002,10]]}},"alternative-id":["S0033291702006177"],"URL":"https:\/\/doi.org\/10.1017\/s0033291702006177","relation":{},"ISSN":["0033-2917","1469-8978"],"issn-type":[{"value":"0033-2917","type":"print"},{"value":"1469-8978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,10]]}}}