{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T02:41:41Z","timestamp":1725504101008},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2003,4,10]],"date-time":"2003-04-10T00:00:00Z","timestamp":1049932800000},"content-version":"unspecified","delay-in-days":9,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2003,4]]},"abstract":"<jats:p><jats:bold>Background.<\/jats:bold> Transsexualism is thought to be related to cortical processes reflecting a complex mosaic of biological, psychological and social\/cultural information. Since the P300 component of event-related potentials is considered as an index of attentional processes, the present study focuses on auditory P300 elicited during a short memory test in male to female (MF) transsexuals, compared with that in healthy controls.<\/jats:p><jats:p><jats:bold>Method.<\/jats:bold> The P300 component was evaluated during the anticipatory period of a short memory test in 13 MF transsexuals who had a gender reassignment operation, at least 3 years previously (mean time 17\u00b76 years, range 3\u201331 years) and 26 healthy subjects (11 males and 15 females) matched for age and educational level.<\/jats:p><jats:p><jats:bold>Results.<\/jats:bold> MF transsexuals exhibited significant reduction of P300 amplitude in the left frontal and temporoparietal areas in comparison to the control group. Furthermore, the group of transsexuals showed a significant delay of P300 latency in comparison to the controls, at the central frontal region.<\/jats:p><jats:p><jats:bold>Conclusions.<\/jats:bold> These findings point to significant psychophysiological alterations of distributed cortical circuits in MF transsexuals. These alterations may be critically related to the biological substrate of MF transsexualism.<\/jats:p>","DOI":"10.1017\/s0033291703007359","type":"journal-article","created":{"date-parts":[[2003,4,24]],"date-time":"2003-04-24T08:38:20Z","timestamp":1051173500000},"page":"555-561","source":"Crossref","is-referenced-by-count":1,"title":["Psychophysiological correlates in male to female transsexuals studied with a P300 investigation"],"prefix":"10.1017","volume":"33","author":[{"given":"C.","family":"PAPAGEORGIOU","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"PAPAGEORGAKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"TOLIS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. D.","family":"RABAVILAS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. N.","family":"CHRISTODOULOU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2003,4,10]]},"container-title":["Psychological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0033291703007359","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,5]],"date-time":"2019-04-05T18:44:23Z","timestamp":1554489863000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0033291703007359\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,4]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2003,4]]}},"alternative-id":["S0033291703007359"],"URL":"https:\/\/doi.org\/10.1017\/s0033291703007359","relation":{},"ISSN":["0033-2917","1469-8978"],"issn-type":[{"value":"0033-2917","type":"print"},{"value":"1469-8978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,4]]}}}