{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T21:14:43Z","timestamp":1774041283904,"version":"3.50.1"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2004,4,21]],"date-time":"2004-04-21T00:00:00Z","timestamp":1082505600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2004,5]]},"abstract":"<jats:p><jats:bold>Background.<\/jats:bold> People with persecutory delusions regard ambiguous data in the social domain as self-relevant and selectively attend to threatening information. This study aimed to characterize these social cognitive biases in functional neuroanatomical terms.<\/jats:p><jats:p><jats:bold>Method.<\/jats:bold> Eight schizophrenic patients with active persecutory delusions and eight matched normal controls underwent functional magnetic resonance imaging while determining the self-relevance of ambiguous self-relevant or unambiguous other-relevant neutral and threatening statements.<\/jats:p><jats:p><jats:bold>Results.<\/jats:bold> In determining self-relevance, the deluded subjects showed a marked absence of rostral\u2013ventral anterior cingulate activation together with increased posterior cingulate gyrus activation in comparison to the normal subjects. The influence of threat on self-relevance determination did not yield statistically significant differences between deluded and normal subjects.<\/jats:p><jats:p><jats:bold>Conclusions.<\/jats:bold> Abnormalities of cingulate gyrus activation while determining self-relevance suggest impaired self-reflection in the persecutory deluded state. This may contribute to persecutory belief formation and maintenance.<\/jats:p>","DOI":"10.1017\/s0033291703008997","type":"journal-article","created":{"date-parts":[[2005,5,10]],"date-time":"2005-05-10T05:31:28Z","timestamp":1115703088000},"page":"591-596","source":"Crossref","is-referenced-by-count":79,"title":["Persecutory delusions and the determination of self-relevance: an fMRI investigation"],"prefix":"10.1017","volume":"34","author":[{"given":"N. J.","family":"BLACKWOOD","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. P.","family":"BENTALL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. H.","family":"FFYTCHE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"SIMMONS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. M.","family":"MURRAY","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. J.","family":"HOWARD","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2004,4,21]]},"container-title":["Psychological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0033291703008997","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T16:30:26Z","timestamp":1554741026000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0033291703008997\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,4,21]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2004,5]]}},"alternative-id":["S0033291703008997"],"URL":"https:\/\/doi.org\/10.1017\/s0033291703008997","relation":{},"ISSN":["0033-2917","1469-8978"],"issn-type":[{"value":"0033-2917","type":"print"},{"value":"1469-8978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,4,21]]}}}