{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T03:58:20Z","timestamp":1777953500138,"version":"3.51.4"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2006,4,20]],"date-time":"2006-04-20T00:00:00Z","timestamp":1145491200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2006,6]]},"abstract":"<jats:p><jats:bold>Background.<\/jats:bold> We tested the hypothesis that depressive symptoms in healthy young adults would be associated with elevated levels of C-reactive proteins (CRP).<\/jats:p><jats:p><jats:bold>Method.<\/jats:bold> We studied the association between depressive symptoms and CRP in 1201 young adults, as a part of the on-going population-based Cardiovascular Risk in Young Finns Study. Depressive symptoms were determined by responses to a revised version of Beck's Depression Inventory in 1992 and 2001. CRP and other known cardiac risk factors were measured in 2001.<\/jats:p><jats:p><jats:bold>Results.<\/jats:bold> Higher depressive symptomatology in 1992 and in 2001 and their means score were related to higher CRP levels (<jats:italic>B<\/jats:italic>'s range from 0\u00b724 to 0\u00b721, <jats:italic>p<\/jats:italic>&lt;0\u00b7001). These relationships persisted after separate adjustments for various risk factors including sex, age, education, oral contraceptive use, dietary fat, physical activity, alcohol consumption, smoking status, LDL-cholesterol, HDL-cholesterol, systolic blood pressure and history of acute infectious disease. Adjustments for obesity and triglycerides levels, however, somewhat attenuated the relationship between depressive symptoms and CRP.<\/jats:p><jats:p><jats:bold>Conclusions.<\/jats:bold> We concluded that higher levels of depressive symptoms are associated with higher levels of CRP, but this association may largely be attributable to obesity or triglycerides.<\/jats:p>","DOI":"10.1017\/s0033291706007574","type":"journal-article","created":{"date-parts":[[2006,4,20]],"date-time":"2006-04-20T08:23:16Z","timestamp":1145521396000},"page":"797-805","source":"Crossref","is-referenced-by-count":75,"title":["Depressive symptoms and C-reactive protein: The Cardiovascular Risk in Young Finns Study"],"prefix":"10.1017","volume":"36","author":[{"given":"MARKO","family":"ELOVAINIO","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LIISA","family":"KELTIKANGAS-J\u00c4RVINEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LAURA","family":"PULKKI-R\u00c5BACK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MIKA","family":"KIVIM\u00c4KI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SAMPSA","family":"PUTTONEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LIISA","family":"VIIKARI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LEENA","family":"R\u00c4S\u00c4NEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KRISTIINA","family":"MANSIKKANIEMI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JORMA","family":"VIIKARI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"OLLI T","family":"RAITAKARI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2006,4,20]]},"container-title":["Psychological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0033291706007574","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T19:36:19Z","timestamp":1554752179000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0033291706007574\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4,20]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["S0033291706007574"],"URL":"https:\/\/doi.org\/10.1017\/s0033291706007574","relation":{},"ISSN":["0033-2917","1469-8978"],"issn-type":[{"value":"0033-2917","type":"print"},{"value":"1469-8978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,4,20]]}}}