{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T08:17:52Z","timestamp":1777537072261,"version":"3.51.4"},"reference-count":38,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2010,9,14]],"date-time":"2010-09-14T00:00:00Z","timestamp":1284422400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:sec id=\"S0033291710001777_sec_a001\"><jats:title>Background<\/jats:title><jats:p>This study prospectively examined the natural clinical course of six anxiety disorders over 7 years of follow-up in individuals with personality disorders (PDs) and\/or major depressive disorder. Rates of remission, relapse, new episode onset and chronicity of anxiety disorders were examined for specific associations with PDs.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291710001777_sec_a002\"><jats:title>Method<\/jats:title><jats:p>Participants were 499 patients with anxiety disorders in the Collaborative Longitudinal Personality Disorders Study, who were assessed with structured interviews for psychiatric disorders at yearly intervals throughout 7 years of follow-up. These data were used to determine probabilities of changes in disorder status for social phobia (SP), generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), panic disorder and panic disorder with agoraphobia.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291710001777_sec_a003\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Estimated remission rates for anxiety disorders in this study group ranged from 73% to 94%. For those patients who remitted from an anxiety disorder, relapse rates ranged from 34% to 67%. Rates for new episode onsets of anxiety disorders ranged from 3% to 17%. Specific PDs demonstrated associations with remission, relapse, new episode onsets and chronicity of anxiety disorders. Associations were identified between schizotypal PD with course of SP, PTSD and GAD; avoidant PD with course of SP and OCD; obsessive-compulsive PD with course of GAD, OCD, and agoraphobia; and borderline PD with course of OCD, GAD and panic with agoraphobia.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291710001777_sec_a004\" sec-type=\"conclusion\"><jats:title>Conclusions<\/jats:title><jats:p>Findings suggest that specific PD diagnoses have negative prognostic significance for the course of anxiety disorders underscoring the importance of assessing and considering PD diagnoses in patients with anxiety disorders.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0033291710001777","type":"journal-article","created":{"date-parts":[[2010,9,14]],"date-time":"2010-09-14T07:12:51Z","timestamp":1284448371000},"page":"1019-1028","source":"Crossref","is-referenced-by-count":78,"title":["The association of personality disorders with the prospective 7-year course of anxiety disorders"],"prefix":"10.1017","volume":"41","author":[{"given":"E. B.","family":"Ansell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. O.","family":"Edelen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. C.","family":"Markowitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. A.","family":"Sanislow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Yen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Zanarini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. E.","family":"Skodol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. T.","family":"Shea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. C.","family":"Morey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. G.","family":"Gunderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. H.","family":"McGlashan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. M.","family":"Grilo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2010,9,14]]},"reference":[{"key":"S0033291710001777_ref035","first-page":"95","article-title":"Phenomenology and epidemiology of panic disorder","volume":"21","author":"Yates","year":"2009","journal-title":"Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists"},{"key":"S0033291710001777_ref028","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-009-0014-0"},{"key":"S0033291710001777_ref024","doi-asserted-by":"publisher","DOI":"10.1007\/s00127-009-0084-7"},{"key":"S0033291710001777_ref003","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.12.2011"},{"key":"S0033291710001777_ref023","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v68n0610"},{"key":"S0033291710001777_ref036","doi-asserted-by":"publisher","DOI":"10.1002\/da.10106"},{"key":"S0033291710001777_ref034","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.s.7002.01"},{"key":"S0033291710001777_ref033","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3956(01)00030-9"},{"key":"S0033291710001777_ref031","doi-asserted-by":"publisher","DOI":"10.1521\/pedi.2005.19.5.487"},{"key":"S0033291710001777_ref037","volume-title":"Diagnostic Interview for DSM-IV Personality Disorders (DIPD-IV)","author":"Zanarini","year":"1996"},{"key":"S0033291710001777_ref017","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1982.04290080031005"},{"key":"S0033291710001777_ref002","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291706007938"},{"key":"S0033291710001777_ref020","doi-asserted-by":"publisher","DOI":"10.1521\/pedi.2000.14.1.57"},{"key":"S0033291710001777_ref038","doi-asserted-by":"publisher","DOI":"10.1521\/pedi.2000.14.4.291"},{"key":"S0033291710001777_ref011","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v68n0511"},{"key":"S0033291710001777_ref029","doi-asserted-by":"publisher","DOI":"10.1002\/anxi.3070010402"},{"key":"S0033291710001777_ref025","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2004.07.015"},{"key":"S0033291710001777_ref026","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2005.00580.x"},{"key":"S0033291710001777_ref013","doi-asserted-by":"publisher","DOI":"10.1521\/pedi.2000.14.4.300"},{"key":"S0033291710001777_ref030","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291705005908"},{"key":"S0033291710001777_ref006","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.6.1179"},{"key":"S0033291710001777_ref001","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1080\/080394899427638","article-title":"A 6-year follow-up study of anxiety disorders in psychiatric outpatients: development and continuity with personality disorders and personality traits as predictors","volume":"53","author":"Aln\u00e6s","year":"1999","journal-title":"Nordic Journal of Psychiatry"},{"key":"S0033291710001777_ref005","doi-asserted-by":"publisher","DOI":"10.1177\/070674370004500506"},{"key":"S0033291710001777_ref012","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.73.1.78"},{"key":"S0033291710001777_ref008","volume-title":"Structured Clinical Interview for DSM-IV Axis I Disorders \u2013 Patient Version (SCID-I\/P)","author":"First","year":"1996"},{"key":"S0033291710001777_ref018","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291705004538"},{"key":"S0033291710001777_ref004","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291706009147"},{"key":"S0033291710001777_ref019","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0447.2000.102004256.x"},{"key":"S0033291710001777_ref022","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.59.5.434"},{"key":"S0033291710001777_ref007","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life tables","volume":"34","author":"Cox","year":"1972","journal-title":"Journal of the Royal Statistical Society Series B (Methodological)"},{"key":"S0033291710001777_ref021","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2006.08.003"},{"key":"S0033291710001777_ref015","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1987.01800180050009"},{"key":"S0033291710001777_ref014","doi-asserted-by":"publisher","DOI":"10.1016\/j.janxdis.2005.06.001"},{"key":"S0033291710001777_ref010","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v66n1102"},{"key":"S0033291710001777_ref027","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-9338(00)00240-6"},{"key":"S0033291710001777_ref009","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2008.41"},{"key":"S0033291710001777_ref032","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(95)00015-W"},{"key":"S0033291710001777_ref016","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1982.04290080025004"}],"container-title":["Psychological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0033291710001777","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,27]],"date-time":"2019-04-27T04:41:27Z","timestamp":1556340087000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0033291710001777\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9,14]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["S0033291710001777"],"URL":"https:\/\/doi.org\/10.1017\/s0033291710001777","relation":{},"ISSN":["0033-2917","1469-8978"],"issn-type":[{"value":"0033-2917","type":"print"},{"value":"1469-8978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9,14]]}}}