{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T09:27:37Z","timestamp":1783330057461,"version":"3.54.6"},"reference-count":61,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T00:00:00Z","timestamp":1567036800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0033291719002186_sec_a1\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Most studies examining predictors of the onset of depression focus on variable centered regression methods that focus on the effects of multiple predictors. In contrast, person-centered approaches develop profiles of factors and these profiles can be examined as predictors of onset. Here, we developed profiles of adolescent psychosocial and clinical functioning among adolescents without a history of major depression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291719002186_sec_a2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data come from a subsample of participants from the Oregon Adolescent Depression Project who completed self-report measures of functioning in adolescence and completed diagnostic and self-report measures at follow-up assessments up to approximately 15 years after baseline.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291719002186_sec_a3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified four profiles of psychosocial and clinical functioning: Thriving; Average Functioning; Externalizing Vulnerability and Family Stress and Internalizing Vulnerability at the baseline assessment of participants without a history of depression at the initial assessment in mid-adolescence. Classes differed in the likelihood of onset and course of depressive disorders, experience of later anxiety and substance use disorders, and psychosocial functioning in adulthood. Moreover, the predictive utility of these classes was maintained when controlling for multiple other established risk factors for depressive disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291719002186_sec_a4\" sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This work highlights the utility of examining multiple factors simultaneously to understand risk for depression.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0033291719002186","type":"journal-article","created":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T03:45:58Z","timestamp":1567050358000},"page":"2066-2074","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":5,"title":["Profiles of psychosocial and clinical functioning in adolescence and risk for later depression and other outcomes"],"prefix":"10.1017","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5139-8571","authenticated-orcid":false,"given":"Thomas M.","family":"Olino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel N.","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Seeley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2019,8,29]]},"reference":[{"key":"S0033291719002186_ref55","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1976.01770090101010"},{"key":"S0033291719002186_ref61","doi-asserted-by":"publisher","DOI":"10.1037\/a0031429"},{"key":"S0033291719002186_ref56","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-197805000-00002"},{"key":"S0033291719002186_ref22","doi-asserted-by":"publisher","DOI":"10.1037\/0033-295X.115.2.291"},{"key":"S0033291719002186_ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s10567-010-0080-1"},{"key":"S0033291719002186_ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2007.01812.x"},{"key":"S0033291719002186_ref45","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.154.11.1593"},{"key":"S0033291719002186_ref35","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291705005350"},{"key":"S0033291719002186_ref54","doi-asserted-by":"publisher","DOI":"10.1037\/abn0000088"},{"key":"S0033291719002186_ref18","doi-asserted-by":"publisher","DOI":"10.1080\/15374416.2012.711708"},{"key":"S0033291719002186_ref29","doi-asserted-by":"publisher","DOI":"10.1097\/CHI.0b013e3181a56606"},{"key":"S0033291719002186_ref26","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.62.6.617"},{"key":"S0033291719002186_ref19","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.107.1.128"},{"key":"S0033291719002186_ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2006.07.001"},{"key":"S0033291719002186_ref27","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.7.709"},{"key":"S0033291719002186_ref32","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.102.1.133"},{"key":"S0033291719002186_ref38","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2000.tb02070.x"},{"key":"S0033291719002186_ref16","doi-asserted-by":"publisher","DOI":"10.1080\/00223891.2013.845201"},{"key":"S0033291719002186_ref49","doi-asserted-by":"publisher","DOI":"10.1037\/a0022621"},{"key":"S0033291719002186_ref12","doi-asserted-by":"publisher","DOI":"10.1037\/10449-000"},{"key":"S0033291719002186_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2017.05.004"},{"key":"S0033291719002186_ref39","volume-title":"Mplus User's Guide","author":"Muth\u00e9n","year":"1998\u20132018"},{"key":"S0033291719002186_ref34","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.112.3.353"},{"key":"S0033291719002186_ref46","doi-asserted-by":"publisher","DOI":"10.1177\/1745691618769868"},{"key":"S0033291719002186_ref14","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2008.41"},{"key":"S0033291719002186_ref33","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-199407000-00006"},{"key":"S0033291719002186_ref9","doi-asserted-by":"publisher","DOI":"10.1037\/a0017205"},{"key":"S0033291719002186_ref11","first-page":"212","volume":"2","author":"Fleiss","year":"1981"},{"key":"S0033291719002186_ref24","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.7.1133"},{"key":"S0033291719002186_ref48","doi-asserted-by":"publisher","DOI":"10.1037\/abn0000232"},{"key":"S0033291719002186_ref7","volume-title":"The Quality of American Life: Perceptions, Evaluations, and Satisfactions","author":"Campbell","year":"1976"},{"key":"S0033291719002186_ref1","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.109.3.403"},{"key":"S0033291719002186_ref2","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"1987"},{"key":"S0033291719002186_ref3","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","year":"1994"},{"key":"S0033291719002186_ref4","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-2253-5"},{"key":"S0033291719002186_ref60","doi-asserted-by":"publisher","DOI":"10.1038\/s41562-016-0005"},{"key":"S0033291719002186_ref8","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.57.1.21"},{"key":"S0033291719002186_ref10","volume-title":"The Structured Clinical Interview for DSM-IV Axis I Disorders","author":"First","year":"1996"},{"key":"S0033291719002186_ref17","doi-asserted-by":"publisher","DOI":"10.1002\/jclp.20293"},{"key":"S0033291719002186_ref20","doi-asserted-by":"publisher","DOI":"10.1002\/da.20224"},{"key":"S0033291719002186_ref21","doi-asserted-by":"publisher","DOI":"10.1177\/2167702614553789"},{"key":"S0033291719002186_ref23","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1987.01800180050009"},{"key":"S0033291719002186_ref25","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.8.789"},{"key":"S0033291719002186_ref28","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291704003587"},{"key":"S0033291719002186_ref30","doi-asserted-by":"publisher","DOI":"10.1037\/a0029567"},{"key":"S0033291719002186_ref31","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1982.04290080001001"},{"key":"S0033291719002186_ref47","first-page":"385","article-title":"Moving beyond main effects: a data analytic strategy for testing complex theories of clinical phenomena","volume":"21","author":"Russell","year":"2014","journal-title":"Clinical Psychology: Science and Practice"},{"key":"S0033291719002186_ref37","unstructured":"Mannuzza, S and Fyer, AJ (1990) Family informant schedule and criteria (FISC), July 1990 revision."},{"key":"S0033291719002186_ref40","doi-asserted-by":"publisher","DOI":"10.1177\/1745691611419672"},{"key":"S0033291719002186_ref41","doi-asserted-by":"publisher","DOI":"10.1080\/10705510701575396"},{"key":"S0033291719002186_ref42","doi-asserted-by":"publisher","DOI":"10.1080\/15374416.2015.1118694"},{"key":"S0033291719002186_ref43","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291707001341"},{"key":"S0033291719002186_ref44","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-7138(09)60944-4"},{"key":"S0033291719002186_ref53","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.113.1.155"},{"key":"S0033291719002186_ref50","doi-asserted-by":"publisher","DOI":"10.1097\/00041444-199324000-00005"},{"key":"S0033291719002186_ref51","doi-asserted-by":"publisher","DOI":"10.1037\/a0028931"},{"key":"S0033291719002186_ref52","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579414000625"},{"key":"S0033291719002186_ref57","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1997.01830220054009"},{"key":"S0033291719002186_ref58","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2016.15101327"},{"key":"S0033291719002186_ref59","volume-title":"The World Health Report 2002-Reducing Risks, Promoting Healthy Life","year":"2002"},{"key":"S0033291719002186_ref5","volume-title":"Auxiliary Variables in Mixture Modeling: Using the BCH Method in Mplus to Estimate a Distal Outcome Model and an Arbitrary Secondary Model","author":"Asparouhov","year":"2014"}],"container-title":["Psychological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0033291719002186","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T05:08:47Z","timestamp":1601442527000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0033291719002186\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,29]]},"references-count":61,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["S0033291719002186"],"URL":"https:\/\/doi.org\/10.1017\/s0033291719002186","relation":{"has-preprint":[{"id-type":"doi","id":"10.31234\/osf.io\/umc2x","asserted-by":"object"}]},"ISSN":["0033-2917","1469-8978"],"issn-type":[{"value":"0033-2917","type":"print"},{"value":"1469-8978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,29]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2019","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}