{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T03:53:08Z","timestamp":1786765988090,"version":"build-2736575974"},"reference-count":56,"publisher":"Cambridge University Press (CUP)","issue":"13","license":[{"start":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T00:00:00Z","timestamp":1606867200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0033291720004316_sec_a1\"><jats:title>Background<\/jats:title><jats:p>Transdiagnostic group cognitive-behavioral therapy (tCBT) is a delivery model that could help overcome barriers to large-scale implementation of evidence-based psychotherapy for anxiety disorders. The aim of this study was to assess the effectiveness of combining group tCBT with treatment-as-usual (TAU), compared to TAU, for the treatment of anxiety disorders in community-based mental health care.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291720004316_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>In a multicenter single-blind, two-arm pragmatic superiority randomized trial, we recruited participants aged 18\u201365 who met DSM-5 criteria for principal diagnoses of generalized anxiety disorder, social anxiety disorder, panic disorder, or agoraphobia. Group tCBT consisted of 12 weekly 2 h sessions. There were no restrictions for TAU. The primary outcome measures were the <jats:italic>Beck Anxiety Inventory<\/jats:italic> (BAI) and clinician severity rating from the <jats:italic>Anxiety and Related Disorders Interview Schedule for DSM-5<\/jats:italic> (ADIS-5) for the principal anxiety disorder at post-treatment, with intention-to-treat analysis.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291720004316_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>A total of 231 participants were randomized to either tCBT + TAU (117) or TAU (114), with outcome data available for, respectively, 95 and 106. Results of the mixed-effects regression models showed superior improvement at post-treatment for participants in tCBT + TAU, compared to TAU, for BAI [<jats:italic>p<\/jats:italic> &lt; 0.001; unadjusted post-treatment mean (<jats:sc>s.d.<\/jats:sc>): 13.20 (9.13) <jats:italic>v.<\/jats:italic> 20.85 (10.96), Cohen's <jats:italic>d<\/jats:italic> = 0.76] and ADIS-5 [<jats:italic>p<\/jats:italic> &lt; 0.001; 3.27 (2.19) <jats:italic>v.<\/jats:italic> 4.93 (2.00), Cohen's <jats:italic>d<\/jats:italic> = 0.79].<\/jats:p><\/jats:sec><jats:sec id=\"S0033291720004316_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>Our findings suggest that the addition of group tCBT into usual care can reduce symptom severity in patients with anxiety disorders, and support tCBT dissemination in routine community-based care.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0033291720004316","type":"journal-article","created":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T08:44:02Z","timestamp":1606898642000},"page":"2460-2470","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":34,"title":["Group transdiagnostic cognitive-behavior therapy for anxiety disorders: a pragmatic randomized clinical trial"],"prefix":"10.1017","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9929-8393","authenticated-orcid":false,"given":"Pasquale","family":"Roberge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin 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