{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T03:21:13Z","timestamp":1794021673519,"version":"4.8.0"},"reference-count":43,"publisher":"Cambridge University Press (CUP)","issue":"14","license":[{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003825","name":"Magyar Tudom\u00e1nyos Akad\u00e9mia","doi-asserted-by":"publisher","award":["J\u00e1nos Bolyai Research Scholarship of the Hungarian Academy of Sciences"],"award-info":[{"award-number":["J\u00e1nos Bolyai Research Scholarship of the Hungarian Academy of Sciences"]}],"id":[{"id":"10.13039\/501100003825","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018818","name":"National Research, Development and Innovation Office","doi-asserted-by":"publisher","award":["OTKA K138385"],"award-info":[{"award-number":["OTKA K138385"]}],"id":[{"id":"10.13039\/501100018818","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0033291723000193_sec_a1\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mood instability and risk-taking are hallmarks of borderline personality disorder (BPD). Schema modes are combinations of self-reflective evaluations, negative emotional states, and destructive coping strategies common in BPD. When activated, they can push patients with BPD into emotional turmoil and a dissociative state of mind. Our knowledge of the underlying neurocognitive mechanisms driving these changes is incomplete. We hypothesized that in patients with BPD, affective instability is more influenced by reward expectation, outcomes, and reward prediction errors (RPEs) during risky decision-making than in healthy controls. Additionally, we expected that these alterations would be related to schema modes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291723000193_sec_a2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty-two patients with BPD and thirty-one healthy controls were recruited. We used an established behavioral paradigm to measure mood fluctuations during risky decision-making. The impact of expectations and RPEs on momentary mood was quantified by a computational model, and its parameters were estimated with hierarchical Bayesian analysis. Model parameters were compared using High-Density Intervals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291723000193_sec_a3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We found that model parameters capturing the influence of RPE and Certain Rewards on mood were significantly higher in patients with BPD than in controls. These model parameters correlated significantly with schema modes, but not with depression severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291723000193_sec_a4\" sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>BPD is coupled with altered associations between mood fluctuation and reward processing under uncertainty. Our findings seem to be BPD-specific, as they stand in contrast with the correlates of depressive symptoms. Future studies should establish the clinical utility of these alterations, such as predicting or assessing therapeutic response in BPD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0033291723000193","type":"journal-article","created":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T23:31:35Z","timestamp":1675899095000},"page":"6714-6723","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":19,"title":["Stronger coupling of emotional instability with reward processing in borderline personality disorder is predicted by schema modes"],"prefix":"10.1017","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5006-9407","authenticated-orcid":false,"given":"G\u00e1bor","family":"Csukly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kinga","family":"Farkas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00edmea","family":"Fodor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsolt","family":"Unoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertalan","family":"Polner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,2,9]]},"reference":[{"key":"S0033291723000193_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00476-1"},{"key":"S0033291723000193_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-405888-0.00014-3"},{"key":"S0033291723000193_ref35","unstructured":"Szalai, D. (2014). Pszichoakt\u00edv szerhaszn\u00e1l\u00f3k maladapt\u00edv s\u00e9m\u00e1i, elker\u00fcl\u0151 megk\u00fczd\u00e9si st\u00edlusa \u00e9s s\u00e9mam\u00f3djai. Department of Behavioural Sciences, Faculty of Public Health: University of Debrecen."},{"key":"S0033291723000193_ref31","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20800"},{"key":"S0033291723000193_ref36","doi-asserted-by":"publisher","DOI":"10.1521\/pedi_2012_26_093"},{"key":"S0033291723000193_ref38","unstructured":"Valton, V. , Wise, T. , & Robinson, O. J. (2020). 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Author(s), 2023. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}