{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:14:26Z","timestamp":1787062466206,"version":"build-2736575974"},"reference-count":42,"publisher":"Cambridge University Press (CUP)","issue":"14","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009321","name":"icare","doi-asserted-by":"publisher","award":["n\/a"],"award-info":[{"award-number":["n\/a"]}],"id":[{"id":"10.13039\/501100009321","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0033291723000338_sec_a1\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mental health and functional difficulties are highly comorbid across neurological disorders, but supportive care options are limited. This randomised controlled trial assessed the efficacy of a novel transdiagnostic internet-delivered psychological intervention for adults with neurological disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291723000338_sec_a2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      221 participants with a confirmed diagnosis of epilepsy, multiple sclerosis, Parkinson's disease, or an acquired brain injury were allocated to either an immediate treatment group (\n                      <jats:italic>n<\/jats:italic>\n                      = 115) or treatment-as-usual waitlist control (\n                      <jats:italic>n<\/jats:italic>\n                      = 106). The intervention, the Wellbeing Neuro Course, was delivered online via the eCentreClinic website. The Course includes six lessons, based on cognitive behavioural therapy, delivered over 10 weeks with support from a psychologist via email and telephone. Primary outcomes were symptoms of depression (PHQ-9), anxiety (GAD-7) and disability (WHODAS 2.0).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291723000338_sec_a3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      215 participants commenced the trial (treatment\n                      <jats:italic>n<\/jats:italic>\n                      = 111; control\n                      <jats:italic>n<\/jats:italic>\n                      = 104) and were included in intention-to-treat analysis. At post-treatment, we observed significant between-group differences in depression (PHQ-9; difference = 3.07 [95% CI 2.04\u20134.11],\n                      <jats:italic>g<\/jats:italic>\n                      = 0.62), anxiety (GAD-7; difference = 1.87 [0.92\u20132.81],\n                      <jats:italic>g<\/jats:italic>\n                      = 0.41) and disability (WHODAS 2.0 difference = 3.08 [1.09\u20135.06],\n                      <jats:italic>g<\/jats:italic>\n                      = 0.31), that favoured treatment (all ps &lt; 0.001). Treatment-related effects were maintained at 3-month follow-up. Findings were achieved with minimal clinician time (average of 95.7 min [\n                      <jats:sc>s.d.<\/jats:sc>\n                      = 59.3] per participant), highlighting the public health potential of this approach to care. No adverse treatment events were reported.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291723000338_sec_a4\" sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Internet-delivered psychological interventions could be a suitable model of accessible supportive care for patients with neurological disorders.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0033291723000338","type":"journal-article","created":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T08:49:47Z","timestamp":1677660587000},"page":"6817-6827","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":15,"title":["The wellbeing neuro course: a randomised controlled trial of an internet-delivered transdiagnostic psychological intervention for adults with neurological disorders"],"prefix":"10.1017","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2161-3298","authenticated-orcid":false,"given":"Milena","family":"Gandy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreea I.","family":"Heriseanu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya","family":"Balakumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eyal","family":"Karin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennie","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor","family":"Hathway","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madelyne A.","family":"Bisby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelia J.","family":"Scott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Dudeney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alana","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nickolai","family":"Titov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blake F.","family":"Dear","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,3,1]]},"reference":[{"key":"S0033291723000338_ref40","unstructured":"WHO. 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Retrieved from https:\/\/www.who.int\/publications\/m\/item\/intersectoral-global-action-plan-on-eepilepsy-and-other-neurological-disorders-2022-2031."},{"key":"S0033291723000338_ref18","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000002606"},{"key":"S0033291723000338_ref32","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2010.230862"},{"key":"S0033291723000338_ref27","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"S0033291723000338_ref10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0264116"},{"key":"S0033291723000338_ref30","doi-asserted-by":"publisher","DOI":"10.1111\/epi.14673"},{"key":"S0033291723000338_ref33","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617712000379"}],"container-title":["Psychological Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0033291723000338","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T03:57:23Z","timestamp":1698292643000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0033291723000338\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,1]]},"references-count":42,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["S0033291723000338"],"URL":"https:\/\/doi.org\/10.1017\/s0033291723000338","relation":{},"ISSN":["0033-2917","1469-8978"],"issn-type":[{"value":"0033-2917","type":"print"},{"value":"1469-8978","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,1]]},"assertion":[{"value":"Copyright \u00a9 The Author(s), 2023. 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