{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:39:36Z","timestamp":1789681176350,"version":"4.0.1"},"reference-count":44,"publisher":"Cambridge University Press (CUP)","issue":"16","license":[{"start":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T00:00:00Z","timestamp":1685318400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0033291723001393_sec_a1\"><jats:title>Background<\/jats:title><jats:p>Negative symptoms (avolition, anhedonia, asociality) are a prevalent symptom in those across the psychosis-spectrum and also occur at subclinical levels in the general population. Recent work has begun to examine how environmental contexts (e.g. locations) influence negative symptoms. However, limited work has evaluated how environments may contribute to negative symptoms among youth at clinical high risk for psychosis (CHR). The current study uses Ecological Momentary Assessment to assess how four environmental contexts (locations, activities, social interactions, social interaction method) impact state fluctuations in negative symptoms in CHR and healthy control (CN) participants.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291723001393_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>CHR youth (<jats:italic>n<\/jats:italic>= 116) and CN (<jats:italic>n<\/jats:italic>= 61) completed 8 daily surveys for 6 days assessing negative symptoms and contexts.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291723001393_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Mixed-effects modeling demonstrated that negative symptoms largely varied across contexts in both groups. CHR participants had higher negative symptoms than CN participants in most contexts, but groups had similar symptom reductions during recreational activities and phone call interactions. Among CHR participants, negative symptoms were elevated in several contexts, including studying\/working, commuting, eating, running errands, and being at home.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291723001393_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>Results demonstrate that negative symptoms dynamically change across some contexts in CHR participants. Negative symptoms were more intact in some contexts, while other contexts, notably some used to promote functional recovery, may exacerbate negative symptoms in CHR. Findings suggest that environmental factors should be considered when understanding state fluctuations in negative symptoms among those at CHR participants.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0033291723001393","type":"journal-article","created":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T09:21:53Z","timestamp":1685352113000},"page":"7609-7618","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":16,"title":["Environmental context predicts state fluctuations in negative symptoms in youth at clinical high risk for psychosis"],"prefix":"10.1017","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2637-4361","authenticated-orcid":false,"given":"Lauren","family":"Luther","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian M.","family":"Raugh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delaney E.","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alysia","family":"Berglund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna R.","family":"Knippenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay A.","family":"Mittal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine F.","family":"Walker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory P.","family":"Strauss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,5,29]]},"reference":[{"key":"S0033291723001393_ref34","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2021.655471"},{"key":"S0033291723001393_ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2013.06.007"},{"key":"S0033291723001393_ref42","doi-asserted-by":"publisher","DOI":"10.3109\/00048679609062654"},{"key":"S0033291723001393_ref44","first-page":"1","article-title":"Conversion to psychosis in adolescents and adults: Similar proportions, different predictors","author":"Zhang","year":"2020","journal-title":"Psychological Medicine"},{"key":"S0033291723001393_ref14","doi-asserted-by":"publisher","DOI":"10.3758\/BF03192848"},{"key":"S0033291723001393_ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.scog.2017.12.001"},{"key":"S0033291723001393_ref21","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.schbul.a007040"},{"key":"S0033291723001393_ref9","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2005.7.1\/kdean"},{"key":"S0033291723001393_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2023.02.037"},{"key":"S0033291723001393_ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2012.02.018"},{"key":"S0033291723001393_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2019.03.017"},{"key":"S0033291723001393_ref39","doi-asserted-by":"publisher","DOI":"10.1037\/0033-295X.104.4.667"},{"key":"S0033291723001393_ref3","volume-title":"Schizophrenia: Cognitive theory, research, and therapy","author":"Beck","year":"2009"},{"key":"S0033291723001393_ref4","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: A practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"Journal of the Royal Statistical Society: Series B (Methodological)"},{"key":"S0033291723001393_ref5","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04250yel"},{"key":"S0033291723001393_ref8","volume-title":"Statistical power analysis for the behavioral sciences","author":"Cohen","year":"1988"},{"key":"S0033291723001393_ref41","doi-asserted-by":"publisher","DOI":"10.1192\/bjo.2019.64"},{"key":"S0033291723001393_ref16","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sby033"},{"key":"S0033291723001393_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2017.08.013"},{"key":"S0033291723001393_ref25","doi-asserted-by":"publisher","DOI":"10.1017\/S2045796021000251"},{"key":"S0033291723001393_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2007.04.009"},{"key":"S0033291723001393_ref30","doi-asserted-by":"publisher","DOI":"10.1111\/2041-210X.13434"},{"key":"S0033291723001393_ref33","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291701005141"},{"key":"S0033291723001393_ref13","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbx080"},{"key":"S0033291723001393_ref10","unstructured":"First, M. 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