{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:04:57Z","timestamp":1791317097508,"version":"4.3.1"},"reference-count":36,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T00:00:00Z","timestamp":1693785600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007502","name":"Stichting tot Steun Vereniging tot Christelijke Verzorging van Geestes- en Zenuwzieken","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007502","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0033291723002143_sec_a1\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Twice weekly sessions of cognitive behavioral therapy (CBT) and interpersonal psychotherapy (IPT) for major depressive disorder (MDD) lead to less drop-out and quicker and better response compared to once weekly sessions at posttreatment, but it is unclear whether these effects hold over the long run.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291723002143_sec_a2\">\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      Compare the effects of twice weekly\n                      <jats:italic>v.<\/jats:italic>\n                      weekly sessions of CBT and IPT for depression up to 24 months since the start of treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291723002143_sec_a3\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using a 2 \u00d7 2 factorial design, this multicentre study randomized 200 adults with MDD to once or twice weekly sessions of CBT or IPT over 16\u201324 weeks, up to a maximum of 20 sessions. Main outcome measures were depression severity, measured with the Beck Depression Inventory-II and the Longitudinal Interval Follow-up Evaluation. Intention-to-treat analyses were conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291723002143_sec_a4\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared with patients who received once weekly sessions, patients who received twice weekly sessions showed a significant decrease in depressive symptoms up through month 9, but this effect was no longer apparent at month 24. Patients who received CBT showed a significantly larger decrease in depressive symptoms up to month 24 compared to patients who received IPT, but the between-group effect size at month 24 was small. No differential effects between session frequencies or treatment modalities were found in response or relapse rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291723002143_sec_a5\" sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although a higher session frequency leads to better outcomes in the acute phase of treatment, the difference in depression severity dissipated over time and there was no significant difference in relapse.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0033291723002143","type":"journal-article","created":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T05:59:45Z","timestamp":1693807185000},"page":"517-526","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":6,"title":["Long-term outcomes of once weekly\n                    <i>v.<\/i>\n                    twice weekly sessions of cognitive behavioral therapy and interpersonal psychotherapy for depression"],"prefix":"10.1017","volume":"54","author":[{"given":"Sanne J. E.","family":"Bruijniks","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D.","family":"Hollon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lotte H. J. M.","family":"Lemmens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frenk P. M. 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