{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:53:43Z","timestamp":1790790823298,"version":"4.1.0"},"reference-count":57,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T00:00:00Z","timestamp":1694649600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0033291723002568_sec_a1\"><jats:title>Background<\/jats:title><jats:p>This study aimed to investigate mother\u2013infant interaction and infant development in women at-risk of postpartum psychosis (PP), with and without a postpartum relapse.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291723002568_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>103 women (and their offspring) were included, 43 at-risk-of-PP because of a diagnosis of bipolar disorder, schizoaffective disorder or previous PP, and 60 with no current\/previous mental illness or family history of PP. Of the at-risk women, 18 developed a psychiatric relapse within 4 weeks after delivery (AR-unwell), while 25 remained symptom-free (AR-well). Mother\u2013infant interaction was assessed using the CARE-Index at 8 weeks' and 12 months' postpartum and infant development using the Bayley-III at 12 months' postpartum.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291723002568_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Women at-risk-of-PP as a group, regardless of whether they developed a psychiatric relapse within 4 weeks after delivery, had less synchronous mother\u2013infant interactions and had infants with less optimal cognitive, language, motor and socio-emotional development than healthy controls. In particular, boys of at-risk women had the lowest scores in cognitive, language and motor development and in mother\u2013infant interaction, while girls of the at-risk women had the lowest scores in socio-emotional development. The synchrony in the dyad predicted infant cognitive and language development. There was no evidence for a difference in mother\u2013infant interaction nor in infant development between the AR-unwell and AR-well groups.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291723002568_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>These results suggest that, while there is a lack of evidence that an early postpartum relapse in women at-risk-of-PP could represent a risk for the infant <jats:italic>per se<\/jats:italic>, maternal risk for PP may be associated with less optimal mother\u2013infant interaction and infant development.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0033291723002568","type":"journal-article","created":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T15:40:38Z","timestamp":1694706038000},"page":"823-834","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":11,"title":["Mother\u2013infant interaction and infant development in women at risk of postpartum psychosis with and 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