{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:18:17Z","timestamp":1791332297008,"version":"4.3.1"},"reference-count":65,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T00:00:00Z","timestamp":1725580800000},"content-version":"unspecified","delay-in-days":36,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S0033291724001375_sec_a1\"><jats:title>Background<\/jats:title><jats:p>Although numerous studies have examined the effects of psychological treatments for obsessive-compulsive disorder (OCD), their overall effectiveness remains unclear. We aimed to estimate their overall effect by combining all available randomized controlled trials (RCTs) comparing psychological treatments to control groups for OCD.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291724001375_sec_a2\" sec-type=\"methods\"><jats:title>Methods<\/jats:title><jats:p>We conducted a meta-analysis of 48 RCTs with 55 comparisons published between 1992 and 1 January 2023. The primary outcome was OCD symptom severity, with Hedges' g calculated at post-treatment and follow-up. Random-effects models were employed for all analyses, and the risk of bias was assessed.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291724001375_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>In general, psychological treatments demonstrated a significantly large effect (<jats:italic>g<\/jats:italic> = \u22121.14; 95% CI [\u22121.31 to \u22120.97]; <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> = 72.23%) on reducing OCD symptom severity post-treatment, this finding remained consistent across measures and after excluding outliers, but lost significance in the sensitivity analysis for only studies with low risk of bias. Type of treatment, control group and treatment format were associated with treatment effects. Moreover, more severe baseline OCD symptom severity predicted higher degree of treatment efficacy. No significant differences were observed in dropout rates between the treatment and control groups. Treatment effects lost significance at 3\u20136 and 6\u201312 month follow-ups. 87% of RCTs were rated at high risk of bias.<\/jats:p><\/jats:sec><jats:sec id=\"S0033291724001375_sec_a4\" sec-type=\"conclusions\"><jats:title>Conclusions<\/jats:title><jats:p>Psychological treatments are effective in reducing OCD symptom severity. However, caution should be exercised when interpreting these results due to the high heterogeneity and risk of bias across RCTs. Future studies with more rigorous methodology are required, as well as studies examining their long-term effectiveness.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s0033291724001375","type":"journal-article","created":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T05:41:15Z","timestamp":1725601275000},"page":"2838-2851","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":18,"title":["The effectiveness of psychological treatments for obsessive-compulsive disorders: a meta-analysis of randomized controlled trials published over last 30 years"],"prefix":"10.1017","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2218-3237","authenticated-orcid":false,"given":"Yingying","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Miguel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marketa","family":"Ciharova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arpana","family":"Amarnath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyuan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiying","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marieke B.J.","family":"Toffolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sascha Y.","family":"Struijs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonore M.","family":"de Wit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pim","family":"Cuijpers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2024,9,6]]},"reference":[{"key":"S0033291724001375_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbtep.2015.02.009"},{"key":"S0033291724001375_ref28","volume-title":"Statistical methods for meta-analysis","author":"Hedges","year":"2014"},{"key":"S0033291724001375_ref59","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2003.08.007"},{"key":"S0033291724001375_ref40","doi-asserted-by":"publisher","DOI":"10.1037\/a0031865"},{"key":"S0033291724001375_ref37","doi-asserted-by":"publisher","DOI":"10.1007\/s10567-019-00296-y"},{"key":"S0033291724001375_ref32","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39343.408449.80"},{"key":"S0033291724001375_ref16","doi-asserted-by":"publisher","DOI":"10.1111\/j.0006-341X.2000.00455.x"},{"key":"S0033291724001375_ref35","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2019.02500"},{"key":"S0033291724001375_ref44","first-page":"78","article-title":"A preliminary study on the effects of attachment-based intervention on pediatric obsessive-compulsive disorder","volume":"4","author":"Rezvan","year":"2013","journal-title":"International journal of preventive medicine"},{"key":"S0033291724001375_ref6","unstructured":"Baer, L. , & Minichiello, W. 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