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However, previous research syntheses addressing the effect of cognitive behavioral therapy (CBT) on RNT are limited to specific diagnoses, treatments, or RNT constructs (transdiagnostic RNT, worry, rumination). In the present meta-analysis, we integrate findings from randomized controlled trials (RCTs) of CBT on RNT across diagnoses, intervention types, and RNT constructs. We investigate the following questions: What is the overall transdiagnostic efficacy of CBT interventions on all post-treatment RNT outcomes? Which RNT construct is addressed most effectively? Are RNT-specific treatments superior in reducing RNT than less specific approaches? Inclusion criteria were met by 55 studies with a total of 4,970 participants. The overall post-treatment effect of CBT interventions on RNT compared to respective control groups was moderate in favor of CBT (<jats:italic>g<\/jats:italic>\u00a0=\u00a0\u22120.67). Treatment efficacy did not differ significantly by RNT construct. RNT-specific interventions (<jats:italic>g<\/jats:italic>\u00a0=\u00a0\u22120.99) were significantly more efficacious in reducing RNT than less specific approaches (<jats:italic>g<\/jats:italic>\u00a0=\u00a0\u22120.56). Treatment efficacy was not significantly enhanced by individual or in-person settings. Our results advocate a dissemination of RNT-specific treatments in research and practice and a general improvement of CBT treatments by focusing on relevant transdiagnostic processes such as RNT.<\/jats:p>","DOI":"10.1017\/s0033291725000017","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T06:52:02Z","timestamp":1738911122000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":28,"title":["Efficacy of cognitive behavioral therapy in treating repetitive negative thinking, rumination, and worry \u2013 a transdiagnostic meta-analysis"],"prefix":"10.1017","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9115-5354","authenticated-orcid":false,"given":"Kilian 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