{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T22:39:45Z","timestamp":1793659185131,"version":"4.5.1"},"reference-count":45,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:00:00Z","timestamp":1755216000000},"content-version":"unspecified","delay-in-days":226,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Psychol. Med."],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"S0033291725101281_sec1\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Depression and anxiety are prevalent mental health disorders. While sleep duration has been extensively studied, sleep regularity may play a critical role. We aimed to examine associations between objectively measured sleep regularity and incident depression and anxiety and to investigate whether meeting recommended sleep duration modifies these associations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291725101281_sec2\" sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In 79,666 UK Biobank participants without baseline depression or anxiety, wrist accelerometers worn for 7\u00a0days yielded a sleep regularity index (SRI) and average sleep duration. SRI was categorized as irregular (\u226451), moderately irregular (52\u201370), or regular (\u226571). Sleep duration was classified by age-specific recommendations (7\u20139\u00a0hours for ages 18\u201364 years; 7\u20138\u00a0hours for over 65 years). Cox regression models assessed associations between sleep parameters and mental health outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291725101281_sec3\" sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>During a median follow-up of 7.5\u00a0years, 1,646 participants developed depression, and 2,097 developed anxiety. Compared to irregular sleepers, regular sleepers had a 38% lower depression risk (hazard ratio [HR], 0.62; 95% confidence interval [CI], 0.52\u20130.73) and a 33% lower anxiety risk (HR, 0.67; 95%CI, 0.58\u20130.77). Participants with both irregular sleep and nonrecommended duration exhibited the highest risks (depression HR, 1.91; 95%CI, 1.55\u20132.35; anxiety HR, 1.61; 95%CI, 1.35\u20131.93). Notably, irregular sleepers who met duration guidelines still faced elevated risks (depression HR, 1.48; 95%CI, 1.18\u20131.86; anxiety HR, 1.35; 95%CI, 1.11\u20131.64).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"S0033291725101281_sec4\" sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Greater sleep regularity is independently associated with lower depression and anxiety risk regardless of sleep duration, suggesting that sleep\u2013wake consistency should be considered in mental health promotion strategies alongside traditional sleep duration recommendations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1017\/s0033291725101281","type":"journal-article","created":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T07:49:38Z","timestamp":1755244178000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":17,"title":["Regular sleep patterns, not just duration, critical for mental health: association of accelerometer-derived sleep regularity with incident depression and anxiety"],"prefix":"10.1017","volume":"55","author":[{"given":"Dong-Run","family":"Li","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0202bj006","id-type":"ROR","asserted-by":"publisher"}],"name":"Shengjing Hospital of China Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng-Xuan","family":"Li","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0202bj006","id-type":"ROR","asserted-by":"publisher"}],"name":"Shengjing Hospital of China Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Hui","family":"Li","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0202bj006","id-type":"ROR","asserted-by":"publisher"}],"name":"Shengjing Hospital of China Medical University"},{"name":"China Medical 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Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e239"}}